Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, an infectious
disease with one of the highest morbidity and mortality rates worldwide. Leveraging its …

The surface finishing techniques can be divided into two categories: traditional and
advanced. To overcome some of the problems of traditional finishing techniques, hybridized …

The pathophysiological understanding of tuberculosis is growing, and with this growth
comes the possibility of applying established pharmaceuticals in new ways. These new …

Tuberculosis is a disease that remains a significant threat to public health worldwide, and
this is mainly due to the selection of strains increasingly resistant to Mycobacterium …

1. Introduction 2. Computational tools for studying M. tuberculosis β-carbonic anhydrases 3.
Molecular biology 4. β-CA1 is induced during environmental stress 5. β-CA2 is essential for …

Pyrazinamide (PZA) is considered to be a pivotal drug to shorten the treatment of both drug-
susceptible and drug-resistant tuberculosis, but its use is challenged by the reliability of drug …

The inappropriate and inconsistent use of antibiotics in combating multidrug-resistant
bacteria exacerbates their drug resistance through a few distinct pathways. Firstly, these …

Tuberculosis (TB) is one of the leading infectious diseases of global concern, and one
quarter of the world's population are TB carriers. Biotin metabolism appears to be an …

Despite decades of research in drug development against TB, it is still the leading cause of
death due to infectious diseases. The long treatment duration, patient noncompliance …

The CYP124 and CYP142 families of bacterial cytochrome P450 monooxygenases (CYPs),
catalyze the oxidation of methyl branched lipids, including cholesterol, as one of the initial …