Atovaquone is used as a fixed-dose combination with proguanil (Malarone) for treating
children and adults with uncomplicated malaria or as chemoprophylaxis for preventing …

The cytochrome bc1 complex is a key component of the mitochondrial respiratory chains of
many eukaryotic microorganisms that are pathogenic for plants or humans, such as fungi …

Health: Deborah Assayag, Elizabeth Barnett, Jennifer Blake, Beverly Brockest, Giovani
Burgos, Glenn Campbell, Andrea Chambers, Angie Chan, Maryann Cheetham, Walter …

Atovaquone, a substituted hydroxynaphthoquinone, is a potent antimalarial drug that acts by
inhibiting the parasite's mitochondrial cytochrome bc 1 complex (cyt bc 1). Mutations in cyt …

The antimicrobial medication malarone (atovaquone/proguanil) is used as a fixed-dose
combination for treating children and adults with uncomplicated malaria or as …

Background Atovaquone/proguanil, registered as Malarone®, is a fixed-dose combination
recommended for first-line treatment of uncomplicated Plasmodium falciparum malaria in …

The risk of malaria for travelers varies from region to region and depends on the intensity of
transmission, the duration of the stay in the area of endemicity, the style of travel, and the …

Antifolates, inhibitors of folate synthesis or folate conversion, are used for malaria treatment.
They are developed as synergistic combinations of inhibitors of dihydrofolate reductase …

Importance of the field: Malaria infection during pregnancy is a major public health problem
worldwide, with 50 million pregnancies exposed to the infection every year. Approximately …

Introduction: Antimalarial drugs are the primary weapon to treat parasite infection, save lives,
and curtail further transmission. Accumulating data have indicated that at least some …