MicroRNA as biomarkers and diagnostics

J Wang, J Chen, S Sen - Journal of cellular physiology, 2016 - Wiley Online Library
MicroRNAs (miRNAs) are a group of small non‐coding RNAs that are involved in regulating
a range of developmental and physiological processes; their dysregulation has been …

[HTML][HTML] miR-122–a key factor and therapeutic target in liver disease

S Bandiera, S Pfeffer, TF Baumert, MB Zeisel - Journal of hepatology, 2015 - Elsevier
Being the largest internal organ of the human body with the unique ability of self-
regeneration, the liver is involved in a wide variety of vital functions that require highly …

MicroRNAs: biomarkers, diagnostics, and therapeutics

W Huang - Bioinformatics in MicroRNA research, 2017 - Springer
MicroRNAs (miRNAs) are small noncoding RNAs (21–23 nucleotides in length) that regulate
gene expression at translational or posttranslational levels. The major regulatory …

Molecular and functional roles of microRNAs in the progression of hepatocellular carcinoma—a review

K Oura, A Morishita, T Masaki - International Journal of Molecular …, 2020 - mdpi.com
Liver cancer is the fourth leading cause of cancer deaths globally, of which hepatocellular
carcinoma (HCC) is the major subtype. Viral hepatitis B and C infections, alcohol abuse, and …

Hepatitis B virus cccDNA: Formation, regulation and therapeutic potential

Y Xia, H Guo - Antiviral research, 2020 - Elsevier
Hepatitis B virus (HBV) infection remains a major public health concern worldwide with
about 257 million individuals chronically infected. Current therapies can effectively control …

MicroRNAs as biomarkers for liver disease and hepatocellular carcinoma

CN Hayes, K Chayama - International journal of molecular sciences, 2016 - mdpi.com
Serum levels of liver enzymes, such as alanine transaminase, aspartate transaminase, and
α-fetoprotein, provide insight into liver function and are used during treatment of liver …

Occult HBV infection

G Raimondo, T Pollicino - Hepatitis B virus in human diseases, 2016 - Springer
The long-lasting persistence of HBV genomes in the liver (and in some cases also in the
serum) of HBsAg negative subjects is termed occult HBV infection (OBI). This peculiar …

[PDF][PDF] MicroRNAs in human diseases: from cancer to cardiovascular disease

TY Ha - Immune network, 2011 - synapse.koreamed.org
The great discovery of microRNAs (miRNAs) has revolutionized current cell biology and
medical science. miRNAs are small conserved non-coding RNA molecules that post …

Human microRNA hsa-miR-296-5p suppresses enterovirus 71 replication by targeting the viral genome

Z Zheng, X Ke, M Wang, S He, Q Li, C Zheng… - Journal of …, 2013 - Am Soc Microbiol
ABSTRACT Enterovirus 71 (EV71) has emerged as a major cause of neurological disease
following the near eradication of poliovirus. Accumulating evidence suggests that …

Computational analysis of targeting SARS-CoV-2, viral entry proteins ACE2 and TMPRSS2, and interferon genes by host microRNAs

JB Pierce, V Simion, B Icli, D Perez-Cremades… - Genes, 2020 - mdpi.com
Rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus
responsible for coronavirus disease 2019 (COVID-19), has led to a global pandemic …