Simple Summary Cells respond to genotoxic stress through complex protein pathways
called DNA damage response (DDR). These mechanisms ensure the preservation of …

Genetic and sporadic forms of tauopathies, the most prevalent of which is Alzheimer's
Disease, are a scourge of the aging society, and in the case of genetic forms, can also affect …

Neurodegenerative disorders and cancer may appear unrelated illnesses. Yet,
epidemiologic studies indicate an inverse correlation between their respective incidences …

Background Drug repurposing provides a cost-effective approach to address the need for
breast cancer prevention and therapeutics. We aimed to identify actionable druggable …

Amyloid aggregation results from the self‐assembly of identical aggregation‐prone
sequences into cross‐beta‐sheet structures. The process is best known for its association …

Neurodegenerative disorders are a family of incurable conditions. Among them, Alzheimer's
disease and tauopathies are the most common. Pathological features of these two disorders …

As the population ages, age-related neurodegenerative diseases have become a major
challenge in health science. Currently, the pathology of neurodegenerative diseases, such …

Alzheimer disease (AD) is the most prominent form of dementia and has received
considerable attention due to its growing burden on economic, healthcare and basic societal …

Simple Summary Constant exposure to endogenous and environmental factors induces
oxidative stress and DNA damage. Rare brain disorders caused by defects in DNA repair …

Alzheimer's disease (AD) and type 2 diabetes mellitus (T2DM) are comorbidities that result
from the sharing of common genes. The molecular background of comorbidities can provide …