Immune checkpoints inhibition is a privileged approach to combat cancers and other human
diseases. The TIM-3 (T cell immunoglobulin and mucin-domain containing-3) inhibitory …

The global scope and scale of the SARS-CoV-2 pandemic led to huge amounts of important
data from clinical observations and experimental analyses being collected, in particular …

Simple Summary The costs worldwide of the coronavirus disease 2019 (COVID-19) have
been tremendous. With millions of deaths in different countries, understanding biomarkers is …

The relationship between the PD-L1 (Programmed Death-Ligand 1)/PD-1 pathway, lung
inflammation, and clinical outcomes in acute respiratory distress syndrome (ARDS) is poorly …

(1) Background/Aim: People infected with SARS-CoV-2 may develop COVID-19 in a wide
range of clinical severity. Pulmonary fibrosis is characterized by several grades of chronic …

Much has been written about matrix metalloproteinases (MMPs) in health and disease
conditions, but their roles in the setting of COVID-19 and associated illnesses remain …

The suppression of excessive immune responses is necessary to prevent injury to the body,
but it also allows cancer cells to escape immune responses and proliferate. Programmed …

Tweetable abstract Severe COVID-19 patients display dysregulated expression of
checkpoint molecules PD-1 and its ligand PD-L1, suggesting that these checkpoint …

Introduction Multisystem Inflammatory Syndrome in children (MIS-C) is a serious
inflammatory sequela of SARS-CoV2 infection. The pathogenesis of MIS-C is vague and …

SARS-CoV-2 cell–cell fusion and syncytiation is an emerging pathomechanism in COVID-
19, but the precise factors contributing to the process remain ill-defined. In this study, we …