Role of cell surface hydrophobicity in the pathogenesis of medically-significant fungi

C Danchik, A Casadevall - Frontiers in Cellular and Infection …, 2021 - frontiersin.org
Cell surface hydrophobicity (CSH) is an important cellular biophysical parameter which
affects both cell-cell and cell-surface interactions. In dimorphic fungi, multiple factors …

Life Cycle of Cryptococcus neoformans

Y Zhao, J Lin, Y Fan, X Lin - Annual review of microbiology, 2019 - annualreviews.org
Cryptococcus neoformans is a ubiquitous environmental fungus and an opportunistic
pathogen that causes fatal cryptococcal meningitis. Advances in genomics, genetics, and …

Cryptococcus neoformans: Sex, morphogenesis, and virulence

Y Zhao, X Lin - Infection, Genetics and Evolution, 2021 - Elsevier
Cryptococcus neoformans is a dimorphic fungus that causes lethal meningoencephalitis
mainly in immunocompromised individuals. Different morphotypes enable this …

Blastomycosis—Some progress but still much to learn

MF Pullen, JD Alpern, NC Bahr - Journal of Fungi, 2022 - mdpi.com
Blastomycosis, caused by Blastomyces spp., is an endemic mycosis capable of causing
significant disease throughout the body. Higher rates of infection are seen in the Mississippi …

Inside the Host: Understanding the Evolutionary Trajectories of Intracellular Parasitism

P Bartošová-Sojková, A Butenko… - Annual Review of …, 2024 - annualreviews.org
This review explores the origins of intracellular parasitism, an intriguing facet of symbiosis,
where one organism harms its host, potentially becoming deadly. We focus on three …

How environmental fungi cause a range of clinical outcomes in susceptible hosts

ST Denham, MA Wambaugh, JCS Brown - Journal of molecular biology, 2019 - Elsevier
Environmental fungi are globally ubiquitous and human exposure is near universal.
However, relatively few fungal species are capable of infecting humans, and among fungi …

Cbp1, a fungal virulence factor under positive selection, forms an effector complex that drives macrophage lysis

D Azimova, N Herrera, L Duvenage, M Voorhies… - PLoS …, 2022 - journals.plos.org
Intracellular pathogens secrete effectors to manipulate their host cells. Histoplasma
capsulatum (Hc) is a fungal intracellular pathogen of humans that grows in a yeast form in …

A unique cell wall synthetic response evoked by glucosamine determines pathogenicity-associated fungal cellular differentiation

P Hu, H Ding, L Shen, GJ He, H Liu, X Tian, C Tao… - PLoS …, 2021 - journals.plos.org
The yeast-to-hypha transition is tightly associated with pathogenicity in many human
pathogenic fungi, such as the model fungal pathogen Cryptococcus neoformans, which is …

Blastomycosis

IS Schwartz, CA Kauffman - Seminars in Respiratory and …, 2020 - thieme-connect.com
Blastomycosis is a serious fungal disease of humans and other mammals caused by
environmentally acquired infection with geographically restricted, thermally dimorphic fungi …

Diagnosis of pulmonary infections due to endemic fungi

V Poplin, C Smith, D Milsap, L Zabel, NC Bahr - Diagnostics, 2021 - mdpi.com
Endemic mycoses including Histoplasma, Blastomyces, Coccidioides, Paracoccidioides,
and Talaromyces are dimorphic fungi that can cause a variety of clinical manifestations …