VEGF-targeting drugs for the treatment of retinal neovascularization in diabetic retinopathy

A Arrigo, E Aragona, F Bandello - Annals of medicine, 2022 - Taylor & Francis
Diabetic retinopathy (DR) is the most common microangiopathic complication of diabetes
mellitus, representing a major cause of visual impairment in developed countries …

Anti‐vascular endothelial growth factor for diabetic macular oedema

G Virgili, M Parravano, F Menchini… - Cochrane Database of …, 2014 - cochranelibrary.com
Background Diabetic macular oedema (DMO) is a common complication of diabetic
retinopathy. Although grid or focal laser photocoagulation has been shown to reduce the risk …

Aflibercept, bevacizumab or ranibizumab for diabetic macular oedema: recent clinically relevant findings from DRCR. net Protocol T

S Cai, NM Bressler - Current opinion in ophthalmology, 2017 - journals.lww.com
Aflibercept, bevacizumab or ranibizumab for diabetic macular... : Current Opinion in
Ophthalmology Aflibercept, bevacizumab or ranibizumab for diabetic macular oedema …

[HTML][HTML] Acircularity index and axis ratio of the foveal avascular zone in diabetic eyes and healthy controls measured by optical coherence tomography angiography

BD Krawitz, S Mo, LS Geyman, SA Agemy… - Vision research, 2017 - Elsevier
Given the complexity of the current system used to stage diabetic retinopathy (DR) and the
risks and limitations associated with intravenous fluorescein angiography (IVFA) …

[HTML][HTML] Fundus-controlled perimetry (microperimetry): application as outcome measure in clinical trials

M Pfau, JK Jolly, Z Wu, J Denniss, EM Lad… - Progress in Retinal and …, 2021 - Elsevier
Fundus-controlled perimetry (FCP, also called 'microperimetry') allows for spatially-resolved
mapping of visual sensitivity and measurement of fixation stability, both in clinical practice as …

Systemic safety of prolonged monthly anti–vascular endothelial growth factor therapy for diabetic macular edema: a systematic review and meta-analysis

RL Avery, GM Gordon - JAMA ophthalmology, 2016 - jamanetwork.com
Importance Anti–vascular endothelial growth factor (VEGF) therapy is commonly used to
treat numerous retinal conditions and appears safe, yet controversy remains regarding …

[HTML][HTML] Optical coherence tomography angiography analysis of the foveal avascular zone and macular vessel density after anti-VEGF therapy in eyes with diabetic …

KG Falavarjani, NA Iafe, JP Hubschman… - … & visual science, 2017 - iovs.arvojournals.org
Purpose: To evaluate the changes in foveal avascular zone (FAZ) area and the retinal
capillary density after a single intravitreal anti-VEGF injection for macular edema secondary …

Intravitreal therapy for diabetic macular edema: an update

C Furino, F Boscia, M Reibaldi… - Journal of …, 2021 - Wiley Online Library
Diabetic macular edema (DME) represents a prevalent and disabling eye condition. Despite
that DME represents a sight‐threatening condition, it is also among the most accessible to …

Clinical perspectives and trends: microperimetry as a trial endpoint in retinal disease

Y Yang, H Dunbar - Ophthalmologica, 2021 - karger.com
Endpoint development trials are underway across the spectrum of retinal disease. New
validated endpoints are urgently required for the assessment of emerging gene therapies …

Sequential restoration of external limiting membrane and ellipsoid zone after intravitreal anti-VEGF therapy in diabetic macular oedema

S De, S Saxena, A Kaur, AA Mahdi, A Misra, M Singh… - Eye, 2021 - nature.com
Abstract Background/Objectives To study the mechanism of restoration of retinal
photoreceptor ellipsoid zone (EZ), after intravitreal bevacizumab (IVB) therapy, in diabetic …