[HTML][HTML] Managing toxicities with asparaginase-based therapies in adult ALL: Summary of an ESMO Open–Cancer Horizons roundtable discussion

PW Burke, D Hoelzer, JH Park, K Schmiegelow… - ESMO open, 2020 - Elsevier
With recent prospective clinical trials that used paediatric regimens with multiple doses of
pegylated form of asparaginase (PEG asparaginase) in adults reporting significantly …

Asparaginase toxicity in Hispanic adult and pediatric patients with acute lymphoblastic leukemia: current understanding

A Alqahtani, D Alhousari, A Ali… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Asparaginase is essential to chemotherapy regimens for acute lymphoblastic
leukemia (ALL). Survival of patients with ALL has improved since incorporating …

Safety of re‐challenging adults with acute lymphoblastic leukemia with PEG‐asparaginase‐induced severe hypertriglyceridemia when treated with a pediatric …

I Al Nabhani, C Andrews, J Sibai, E Atenafu, T Young… - …, 2023 - Wiley Online Library
PEG‐asparaginase is used as a treatment for Philadelphia‐negative acute lymphoblastic
leukemia. In pediatric studies, triglycerides (TGs) were affected more by PEG‐asparaginase …