COVID19 biomarkers: What did we learn from systematic reviews?

S Semiz - Frontiers in cellular and infection microbiology, 2022 - frontiersin.org
The coronavirus disease 2019 (COVID19) pandemic continues to represent a substantial
public health concern. It can rapidly progress to severe disease, with poor prognosis and a …

The role of neutrophil-to-lymphocyte ratio in risk stratification and prognostication of COVID-19: a systematic review and meta-analysis

A Parthasarathi, S Padukudru, S Arunachal… - Vaccines, 2022 - mdpi.com
Several studies have proposed that the neutrophil–lymphocyte ratio (NLR) is one of the
various biomarkers that can be useful in assessing COVID-19 disease-related outcomes …

D-dimer as a biomarker for assessment of COVID-19 prognosis: D-dimer levels on admission and its role in predicting disease outcome in hospitalized patients with …

A Poudel, Y Poudel, A Adhikari, BB Aryal, D Dangol… - Plos one, 2021 - journals.plos.org
Introduction Coronavirus Disease 2019 is a primarily respiratory illness that can cause
thrombotic disorders. Elevation of D-dimer is a potential biomarker for poor prognosis in …

Neutrophil-to-lymphocyte ratio on admission to predict the severity and mortality of COVID-19 patients: A meta-analysis

DM Simadibrata, J Calvin, AD Wijaya… - The American journal of …, 2021 - Elsevier
Background The neutrophil-to-lymphocyte ratio (NLR), an inflammatory marker, was
suggested to be predictive of severity and mortality in COVID-19 patients. Here, we …

Effective prognostic and clinical risk stratification in COVID‐19 using multimodality biomarkers

A Liu, R Hammond, PD Donnelly… - Journal of Internal …, 2023 - Wiley Online Library
In acute coronavirus disease 19 (COVID‐19) patients, effective clinical risk stratification has
important implications on treatment and therapeutic resource distribution. This article …

Albumin supplementation dampens hypercoagulability in COVID-19: a preliminary report

F Violi, G Ceccarelli, L Loffredo… - Thrombosis and …, 2021 - thieme-connect.com
Coronavirus disease 2019 (COVID-19) is characterized by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) needing mechanical ventilation and intensive care …

Clinical significance of plasma D-dimer in COVID-19 mortality

Y Li, Y Deng, L Ye, H Sun, S Du, H Huang… - Frontiers in …, 2021 - frontiersin.org
It is not clear whether D-dimer can be an independent predictor of coronavirus disease 2019
(COVID-19) mortality, and the cut-off of D-dimer for clinical use remains to be determined …

Severe COVID-19 infection associated with endothelial dysfunction induces multiple organ dysfunction: a review of therapeutic interventions

Y Matsuishi, BJ Mathis, N Shimojo, J Subrina, N Okubo… - Biomedicines, 2021 - mdpi.com
Since December 2019, the SARS-CoV-2 (COVID-19) pandemic has transfixed the medical
world. COVID-19 symptoms vary from mild to severe and underlying chronic conditions such …

Impact of respiratory bacterial infections on mortality in Japanese patients with COVID-19: a retrospective cohort study

K Nakagawara, H Kamata, S Chubachi… - BMC Pulmonary …, 2023 - Springer
Background Although cases of respiratory bacterial infections associated with coronavirus
disease 2019 (COVID-19) have often been reported, their impact on the clinical course …

The clinical significance of ultra-high D-dimer levels

K Schafer, E Goldschmidt, D Oostra, J Fish… - Journal of Vascular …, 2022 - Elsevier
Objective Plasma D-dimer levels> 5000 ng/mL are encountered in a number of conditions
other than venous thromboembolism (VTE). Recent studies have used plasma D-dimer …