Bioinspired polymer vesicles and membranes for biological and medical applications

CG Palivan, R Goers, A Najer, X Zhang, A Car… - Chemical society …, 2016 - pubs.rsc.org
Biological membranes play an essential role in living organisms by providing stable and
functional compartments, preserving cell architecture, whilst supporting signalling and …

Engineering functional polymer capsules toward smart nanoreactors

J Gaitzsch, X Huang, B Voit - Chemical reviews, 2016 - ACS Publications
The design and construction of integrated chemical ensembles for studying complex
biological systems is attracting considerable interest in a wide range of research …

Imparting Functionality to Biocatalysts via Embedding Enzymes into Nanoporous Materials by a de Novo Approach: Size-Selective Sheltering of Catalase in Metal …

FK Shieh, SC Wang, CI Yen, CC Wu… - Journal of the …, 2015 - ACS Publications
We develop a new concept to impart new functions to biocatalysts by combining enzymes
and metal–organic frameworks (MOFs). The proof-of-concept design is demonstrated by …

Amorphous Fe-containing phosphotungstates featuring efficient peroxidase-like activity at neutral pH: toward portable swabs for pesticide detection with tandem …

H Zhu, B Liu, M Wang, J Pan, L Xu, P Hu… - Analytical …, 2023 - ACS Publications
Peroxidase-mimetic materials are intensively applied to establish multienzyme systems
because of their attractive merits. However, almost all of the nanozymes explored exhibit …

Multicompartmentalized polymeric systems: towards biomimetic cellular structure and function

M Marguet, C Bonduelle… - Chemical Society Reviews, 2013 - pubs.rsc.org
The cell is certainly one of the most complex and exciting systems in Nature that scientists
are still trying to fully understand. Such a challenge pushes material scientists to seek to …

Polymeric vesicles: from drug carriers to nanoreactors and artificial organelles

P Tanner, P Baumann, R Enea, O Onaca… - Accounts of chemical …, 2011 - ACS Publications
One strategy in modern medicine is the development of new platforms that combine
multifunctional compounds with stable, safe carriers in patient-oriented therapeutic …

Compartmentalization approaches in soft matter science: from nanoreactor development to organelle mimics

L Schoonen, JCM Van Hest - Advanced Materials, 2016 - Wiley Online Library
Compartmentalization is an essential feature found in living cells to ensure that biological
processes occur without being affected by undesired external influences. Over the years …

Nanozyme‐based artificial organelles: an emerging direction for artificial organelles

S Zhang, R Zhang, X Yan, K Fan - Small, 2022 - Wiley Online Library
Artificial organelles are compartmentalized nanoreactors, in which enzymes or enzyme‐
mimic catalysts exhibit cascade catalytic activities to mimic the functions of natural …

Nanoreactors by programmed enzyme encapsulation inside the capsid of the bacteriophage P22

DP Patterson, PE Prevelige, T Douglas - ACS nano, 2012 - ACS Publications
The virus like particle (VLP) derived from bacteriophage P22 presents a unique platform for
constructing catalytically functional nanomaterials by encapsulation of enzymes into its …

High efficiency and long-term intracellular activity of an enzymatic nanofactory based on metal-organic frameworks

X Lian, A Erazo-Oliveras, JP Pellois, HC Zhou - Nature communications, 2017 - nature.com
Enhancing or restoring enzymatic function in cells is highly desirable in applications ranging
from ex vivo cellular manipulations to enzyme replacement therapies in humans. However …