Since its first approval by the Food and Drug Administration in 1989 for strabismus,
botulinum toxin indications of use have been widely expanded. Due to its anticholinergic …

We systematically identified effective and resource‐efficient strategies for recruiting families
into health promoting intervention research. Four databases were searched for reviews …

Participant recruitment for pediatric palliative intervention studies is a chronic challenge for
researchers. Digital recruitment strategies, or digital technology-assisted recruitment …

Introduction: With the emphasis on patient-centeredness, the interest in examining people's
perceptions of health interventions has resurged. Mounting evidence suggests that people's …

Abstract Background Randomised controlled trials (RCTs) are considered the 'gold
standard'of medical evidence; however, recruitment can be challenging. The MACRO trial is …

METHODS Baseline, 12-month, and 24-month assessments included intellectual ability,
polysomnography, audiology, a pediatric sleep questionnaire, the parent rating scale of the …

Background In paediatric epilepsy, the evidence of effectiveness of antiseizure treatment is
inconclusive for some types of epilepsy. As with other paediatric clinical trials, researchers …

Background Randomized Clinical Trials (RCT) represent the gold standard among scientific
evidence. RCTs are tailored to control selection bias and the confounding effect of baseline …

Introduction Musculoskeletal deformities and gait deviations are common features in
ambulatory cerebral palsy (CP). Deformity correction through lower limb orthopaedic surgery …

Background Family-based physical activity promotion presents a promising avenue for
promoting whole-family physical activity, but high-quality research is lacking. Objectives To …