Phyto-therapeutic and nanomedicinal approaches to cure Alzheimer's disease: present status and future opportunities

M Ovais, N Zia, I Ahmad, AT Khalil, A Raza… - Frontiers in aging …, 2018 - frontiersin.org
Alzheimer's disease (AD) is characterized by cognitive inability manifested due to the
accumulation of β-amyloid, formation of hyper phosphorylated neurofibrillary tangles, and a …

Underlying anticancer mechanisms and synergistic combinations of phytochemicals with cancer chemotherapeutics: potential benefits and risks

M Ayaz, A Nawaz, S Ahmad, OF Mosa… - Journal of Food …, 2022 - Wiley Online Library
Cancer therapies are associated with various challenges including the emergence of
multidrug resistant tumors, toxicological issues, severe side effects, and economic burden …

[HTML][HTML] Design, synthesis and bioevaluation of new vanillin hybrid as multitarget inhibitor of α-glucosidase, α-amylase, PTP-1B and DPP4 for the treatment of type-II …

MA Huneif, DB Alshehri, KS Alshaibari… - Biomedicine & …, 2022 - Elsevier
Diabetes mellitus (DM) is a real challenge to the recent era and is one of the major diseases
for initiating life-threatening disorders. In current research, a compound was designed by …

Phytochemical profiling of bioactive compounds, anti-inflammatory and analgesic potentials of Habenaria digitata Lindl.: Molecular docking based synergistic effect of …

MH Mahnashi, BA Alyami, YS Alqahtani, MS Jan… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Members of Orchidaceae family has a long
history in herbal and Chinese medicines. Members of this family are most commonly famous …

Treating Hyperglycemia From Eryngium caeruleum M. Bieb: In-vitro α-Glucosidase, Antioxidant, in-vivo Antidiabetic and Molecular Docking-Based Approaches

A Sadiq, U Rashid, S Ahmad, M Zahoor… - Frontiers in …, 2020 - frontiersin.org
Natural-based drugs are believed to be safe, effective and economical. Based on the
medicinal importance of the genus Eryngium and unexplored nature of Eryngium …

Anti-Inflammatory, Analgesic and Antioxidant Potential of New (2S,3S)-2-(4-isopropylbenzyl)-2-methyl-4-nitro-3-phenylbutanals and Their Corresponding Carboxylic …

F Mahmood, JA Khan, MH Mahnashi, MS Jan… - Molecules, 2022 - mdpi.com
In the current study, a series of new (2 S, 3 S)-2-(4-isopropylbenzyl)-2-methyl-4-nitro-3-
phenylbutanals (FM1-6) with their corresponding carboxylic acid analogues (FM7-12) has …

Phytochemical analysis, Ephedra Procera CA Mey. Mediated green synthesis of silver nanoparticles, their cytotoxic and antimicrobial potentials

MQ Nasar, AT Khalil, M Ali, M Shah, M Ayaz… - Medicina, 2019 - mdpi.com
Background and Objectives: The current study focuses on an eco-friendly and cost-effective
method of Ephedra procera CA Mey. mediated green synthesis of silver nanoparticles as …

In-vitro, in-vivo, molecular docking and ADMET studies of 2-substituted 3, 7-dihydroxy-4H-chromen-4-one for oxidative stress, inflammation and Alzheimer's disease

MH Mahnashi, MA Alshahrani, MH Nahari, SS Hassan… - metabolites, 2022 - mdpi.com
Plants' bioactives are well-known safe drugs for vital diseases. Flavones and Flavonoid-rich
dietary supplements are known to exhibit neuroprotective potential. In this study, we isolated …

Lawsonia Inermis Markedly Improves Cognitive Functions in Animal Models and Modulate Oxidative Stress Markers in the Brain

NT Mir, U Saleem, F Anwar, B Ahmad, I Ullah, S Hira… - Medicina, 2019 - mdpi.com
Background and Objective: Medicinal plants represent an important source of alternative
medicine for the management of various diseases. The present study was undertaken to …

Green-synthesized zinc oxide nanoparticles, anti-Alzheimer potential and the metabolic profiling of Sabal blackburniana grown in Egypt supported by molecular …

SS El-Hawwary, HM Abd Almaksoud, FR Saber… - RSC …, 2021 - pubs.rsc.org
Nowadays, the biosynthesis of metal nanoparticles, particularly from plants, has been
gaining interest. In the present work, the methanolic extracts of leaves, fruits, and the pollen …