Increases in depressive behaviors have been reported in patients experiencing chronic
pain. In these patients, the symptoms of pain and depression commonly coexist, impairing …

The conceptualization of polycystic ovary syndrome (PCOS) has primarily focused on
hormonal alterations driven by changes within the hypothalamus and ovarian granulosa …

The acute pain induced by clinical procedures, such as venipuncture, dental operations, and
dermatological treatments, as well as postoperative pain, drives the advancement of …

Since sleep is a key homeostatic phenomenon of the body, therefore understanding the
complex etiology of the neurological outcome of sleep deprivation (SD) such as anxiety …

MAO-B inhibitors have been implicated to reverse neuropathic pain behaviors. Our previous
study has demonstrated that KDS2010 (KDS), a newly developed reversible MAO-B …

Mice lacking the σ1 receptor chaperone (σ1R–/–) are resilient to depressive-like behaviors
secondary to neuropathic pain. Examining the resilience's brain mechanisms could help …

Burn injuries can be devastating, with life-long impacts including an increased risk of
hospitalization for a wide range of secondary morbidities. One area that remains not fully …

It is well known that emotions can interfere with the perception of physical pain, as well as
with the development and maintenance of painful conditions. On the other hand, somatic …

Chronic pain research, with a specific focus on the brain-derived neurotrophic factor (BDNF),
has made impressive progress in the past decade, as evident in the improved research …

Purpose The INTERMED instrument, which was developed to measure patient's
biopsychosocial (BPS) complexity, represents a powerful diagnostic and therapeutic tool …