Pancreatic cancer: pathogenesis, screening, diagnosis, and treatment

LD Wood, MI Canto, EM Jaffee, DM Simeone - Gastroenterology, 2022 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is a clinically challenging cancer, due to both its
late stage at diagnosis and its resistance to chemotherapy. However, recent advances in our …

Pancreatic cancer

JD Mizrahi, R Surana, JW Valle, RT Shroff - The Lancet, 2020 - thelancet.com
Pancreatic cancer is a highly fatal disease with a 5-year survival rate of approximately 10%
in the USA, and it is becoming an increasingly common cause of cancer mortality. Risk …

Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma

AJ Grossberg, LC Chu, CR Deig… - CA: a cancer journal …, 2020 - Wiley Online Library
Despite tremendous gains in the molecular understanding of exocrine pancreatic cancer,
the prognosis for this disease remains very poor, largely because of delayed disease …

Efficacy of perioperative chemotherapy for resectable pancreatic adenocarcinoma: a phase 2 randomized clinical trial

DPS Sohal, M Duong, SA Ahmad, NS Gandhi… - JAMA …, 2021 - jamanetwork.com
Importance Clinical outcomes after curative treatment of resectable pancreatic ductal
adenocarcinoma (PDA) remain suboptimal. To assess the potential of early control of …

The North American Neuroendocrine Tumor Society consensus paper on the surgical management of pancreatic neuroendocrine tumors

JR Howe, NB Merchant, C Conrad, XM Keutgen… - Pancreas, 2020 - journals.lww.com
This manuscript is the result of the North American Neuroendocrine Tumor Society
consensus conference on the surgical management of pancreatic neuroendocrine tumors …

Oncological benefits of neoadjuvant chemoradiation with gemcitabine versus upfront surgery in patients with borderline resectable pancreatic cancer: a prospective …

JY Jang, Y Han, H Lee, SW Kim, W Kwon… - Annals of …, 2018 - journals.lww.com
Objective: This study was performed to determine whether neoadjuvant treatment increases
survival in patients with BRPC. Summary Background Data: Despite many promising …

[HTML][HTML] Challenges in diagnosis of pancreatic cancer

L Zhang, S Sanagapalli, A Stoita - World journal of …, 2018 - ncbi.nlm.nih.gov
Pancreatic cancer is a growing source of cancer related death, yet has poor survival rates
which have not improved in the last few decades. Its high mortality rate is attributed to …

Pancreatic adenocarcinoma, version 2.2017, NCCN clinical practice guidelines in oncology

MA Tempero, MP Malafa, M Al-Hawary… - Journal of the National …, 2017 - jnccn.org
Ductal adenocarcinoma and its variants account for most pancreatic malignancies. High-
quality multiphase imaging can help to preoperatively distinguish between patients eligible …

[HTML][HTML] International consensus on definition and criteria of borderline resectable pancreatic ductal adenocarcinoma 2017

S Isaji, S Mizuno, JA Windsor, C Bassi… - Pancreatology, 2018 - Elsevier
This statement was developed to promote international consensus on the definition of
borderline resectable pancreatic ductal adenocarcinoma (BR-PDAC) which was adopted by …

Cancer of the pancreas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

M Ducreux, AS Cuhna, C Caramella… - Annals of …, 2015 - annalsofoncology.org
A recent study estimating cancer epidemiology in 2014 (within Europe) showed that
pancreatic cancer was the fourth most fatal cancer in men after lung, colorectal, and prostate …