Abstract Our previous International Union of Basic and Clinical Pharmacology report on the
nomenclature and classification of adenosine receptors (2011) contained a number of …

The purine alkaloid caffeine is the most widely consumed psychostimulant drug in the world
and has multiple beneficial pharmacological activities, for example, in neurodegenerative …

Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …

Medicinal chemical approaches have been applied to all four of the adenosine receptor
(AR) subtypes (A1, A2A, A2B, and A3) to create selective agonists and antagonists for each …

A. Cellular and Subcellular Localization B. Pharmacological Tools to Study Adenosine
Receptors C. Signaling Via Adenosine Receptors D. Regulation of Receptor Expression and …

A window of opportunity: A general copper‐catalyzed C H bond‐activation path allows
arylation of heterocycles with a wide range of aryl bromides (see scheme). The reaction …

The purine nucleoside adenosine is consensually identified as a major local regulator of
tissue function especially when energy supply fails to meet cellular energy demand. Due to …

Gemischtes Doppel: Bei der hoch regioselektiven C3‐Heteroarylierung eines Indols oder
eines Pyrrols mit einer Vielzahl elektronenreicher und‐armer N‐Heteroarene, für die ein …

A highly effective visible light‐promoted “radical‐type” coupling of N‐heteroarenes with
aryldiazonium salts in water has been developed. The reaction proceeds at room …

Medicinal plants have been the basis for discovery of various important marketed drugs.
Xanthine is one such lead molecule. Xanthines in various forms (caffeine, theophylline …