Understanding pulmonary autograft remodeling after the Ross procedure: stick to the facts

L Van Hoof, P Verbrugghe, EAV Jones… - Frontiers in …, 2022 - frontiersin.org
The Ross, or pulmonary autograft, procedure presents a fascinating mechanobiological
scenario. Due to the common embryological origin of the aortic and pulmonary root, the …

Aortic Valve Embryology, Mechanobiology, and Second Messenger Pathways: Implications for Clinical Practice

ML Notenboom, L Van Hoof, A Schuermans… - Journal of …, 2024 - mdpi.com
During the Renaissance, Leonardo Da Vinci was the first person to successfully detail the
anatomy of the aortic root and its adjacent structures. Ever since, novel insights into …

Hemodynamics and wall shear metrics in a pulmonary autograft: Comparing a fluid-structure interaction and computational fluid dynamics approach

A Balasubramanya, L Maes, F Rega, V Mazzi… - Computers in Biology …, 2024 - Elsevier
Objective In young patients, aortic valve disease is often treated by placement of a
pulmonary autograft (PA) which adapts to its new environment through growth and …

Numerical simulation of fluid-structure interaction analysis for the performance of leaflet reimplantation with different types of artificial graft.

Q Wang, X Luo, J Qiu, S Hu, X Ding, T Du… - Computer Methods and …, 2025 - Elsevier
Abstract Background and Objective: In clinical practice, valve-sparing aortic root
replacement surgery primarily addresses left ventricular dysfunction in patients due to …

Autograft dilation after Ross procedure in children and young adults is mitigated by autograft reinforcement: A retrospective MRI study

R Seiler, R Stenzel, V Weixler, M Muiznieks… - Scientific Reports, 2025 - nature.com
Limited magnetic resonance imaging (MRI) data on autograft dilatation following the Ross
procedure in congenital cohorts presents challenges in understanding its evolution and …

The role of the extracellular matrix in the development of heart valve disease: Underestimation or undercomprehension?

F Nappi - Journal of Cardiac Surgery, 2022 - Wiley Online Library
The function of metalloproteinases of the extracellular matrix and their inhibitors has
emerged with a crucial role in valve diseases. Both the expression of matrix …

Commentary: An opportunity for a new look at the Ross autograft

JL Herrmann - The Journal of Thoracic and Cardiovascular Surgery, 2022 - jtcvs.org
T pulmonary arterial tissues collected at the time of the Ross procedure and were subjected
to ex vivo biaxial stretching to generate patient-specific material properties for modeling …

Commentary: Biomechanical remodeling of the pulmonary autograft after the Ross procedure

G Gaidulis, M Padala - The Journal of Thoracic and Cardiovascular Surgery, 2022 - jtcvs.org
The Ross procedure is a safe and effective aortic valve replacement option for younger
patients with aortic valve disease. Being a living valve substitute, with tissue architecture …