An estimated 20–25% of the population is affected by chronic, non-communicable
inflammatory skin diseases. Chronic skin inflammation has many causes. Among the most …

Autoimmune skin blistering diseases (AIBD) are characterized by autoantibodies that are
directed against structural proteins in the skin and adjacent mucous membranes. Some …

This guideline has been initiated by the task force Autoimmune Blistering Diseases of the
European Academy of Dermatology and Venereology, including physicians from all relevant …

Many ulcerative or vesiculobullous disease of the mouth have a similar clinical appearance.
The oral mucosa is thin, and even slight trauma leads to rupture of vesicles and bullae …

This guideline on mucous membrane pemphigoid (MMP) has been elaborated by the Task
Force for Autoimmune Blistering Diseases of the European Academy of Dermatology and …

Antibodies of IgG4 subclass are exceptional players of the immune system, as they are
considered to be immunologically inert and functionally monovalent, and as such may be …

Autoimmune bullous dermatoses (AIBD) encompass a variety of organ-specific autoimmune
diseases that manifest with cutaneous and/or mucosal blisters and erosions. They are …

Background Paraneoplastic pemphigus (PNP), also called paraneoplastic autoimmune
multiorgan syndrome (PAMS), is a rare autoimmune disease with mucocutaneous and multi …

Laminin 332 is a heterotrimeric structural protein of the basal membrane zone (BMZ) of the
skin and adjacent mucosal tissues. The importance of laminin 332 for the structural integrity …

Mucous membrane pemphigoid (MMP) is a mucous membrane-dominated autoimmune
subepithelial blistering disease that is caused by autoantibodies against various …