Globally, pneumonia is a serious public health concern and a major cause of mortality and
morbidity. Despite advances in antimicrobial therapies, microbiological diagnostic tests and …

Background Pneumococcal pneumonia causes significant morbidity and mortality among
adults. Given limitations of diagnostic tests for non-bacteremic pneumococcal pneumonia …

The first human orthotopic liver transplantation (LT) in Europe was performed by Sir Roy
Calne in Cambridge in 1968 [1], only one year after the first successful human liver …

Objectives We described the current incidence and risk factors of bacterial co-infection in
hospitalized patients with COVID-19. Methods Observational cohort study was performed at …

Context Clinicians order blood cultures liberally among patients in whom bacteremia is
suspected, though a small proportion of blood cultures yield true-positive results. Ordering …

Patients with cirrhosis are immunocompromised and susceptible to infections. Although
detection and treatment of spontaneous bacterial peritonitis (SBP) have improved, overall …

Guidance regarding indications for initial or follow-up blood cultures is limited. We
conducted a scoping review of articles published between January 2004 and June 2019 that …

3. Chest radiograph should be repeated if the patient is not improving and also for all those
patients who have persistence or worsening of symptoms/physical signs or those in whom …

Community-acquired pneumonia is not usually considered a high-priority problem by the
public, although it is responsible for substantial mortality, with a third of patients dying within …

Viable and non-viable pathological bacterial translocation promote a self-perpetuating circle
of dysfunctional immune activation and systemic inflammation facilitating infections and …