Quorum-sensing regulation of virulence factors in bacterial biofilm

A Warrier, K Satyamoorthy, TS Murali - Future microbiology, 2021 - Taylor & Francis
Chronic polymicrobial wound infections are often characterized by the presence of bacterial
biofilms. They show considerable structural and functional heterogeneity, which influences …

The role of antibiotics in modulating virulence in Staphylococcus aureus

E Hodille, W Rose, BA Diep, S Goutelle… - Clinical microbiology …, 2017 - Am Soc Microbiol
Staphylococcus aureus is often involved in severe infections, in which the effects of bacterial
virulence factors have great importance. Antistaphylococcal regimens should take into …

Resistance Evolution Against Antimicrobial Peptides in Staphylococcus aureus Alters Pharmacodynamics Beyond the MIC

B El Shazely, G Yu, PR Johnston, J Rolff - Frontiers in microbiology, 2020 - frontiersin.org
Antimicrobial peptides (AMPs) have been proposed as a promising class of new
antimicrobials partly because they are less susceptible to bacterial resistance evolution. This …

A broad-spectrum synthetic antibiotic that does not evoke bacterial resistance

DM Heithoff, SP Mahan, L Barnes, SA Leyn… - …, 2023 - thelancet.com
Background Antimicrobial resistance (AMR) poses a critical threat to public health and
disproportionately affects the health and well-being of persons in low-income and middle …

Defining motility in the Staphylococci

EJG Pollitt, SP Diggle - Cellular and Molecular Life Sciences, 2017 - Springer
The ability of bacteria to move is critical for their survival in diverse environments and
multiple ways have evolved to achieve this. Two forms of motility have recently been …

RNA-dependent regulation of virulence in pathogenic bacteria

S Chakravarty, E Massé - Frontiers in cellular and infection …, 2019 - frontiersin.org
During infection, bacterial pathogens successfully sense, respond and adapt to a myriad of
harsh environments presented by the mammalian host. This exquisite level of adaptation …

Photoactivated Gallium Porphyrin Reduces Staphylococcus aureus Colonization on the Skin and Suppresses Its Ability to Produce Enterotoxin C and TSST-1

K Szymczak, G Szewczyk, M Rychłowski… - Molecular …, 2023 - ACS Publications
Staphylococcus aureus is a key pathogen in atopic dermatitis (AD) pathogenicity. Over half
of AD patients are carriers of S. aureus. Clinical isolates derived from AD patients produce …

Modulation of MRSA virulence gene expression by the wall teichoic acid enzyme TarO

Y Lu, F Chen, Q Zhao, Q Cao, R Chen, H Pan… - Nature …, 2023 - nature.com
Phenol-soluble modulins (PSMs) and Staphylococcal protein A (SpA) are key virulence
determinants for community-associated methicillin-resistant Staphylococcus aureus (CA …

The Agr Quorum Sensing System Represses Persister Formation through Regulation of Phenol Soluble Modulins in Staphylococcus aureus

T Xu, XY Wang, P Cui, YM Zhang, WH Zhang… - Frontiers in …, 2017 - frontiersin.org
The opportunistic pathogen Staphylococcus aureus has become an increasing threat to
public health. While the Agr quorum sensing (QS) system is a master regulator of S. aureus …

[HTML][HTML] Exotoxin diversity of Staphylococcus aureus isolated from milk of cows with subclinical mastitis in Central Russia

KK Fursova, MP Shchannikova, IV Loskutova… - Journal of dairy …, 2018 - Elsevier
Mastitis, a major veterinary problem widespread in many regions, is caused mainly by
Staphylococcus spp. However, there is no current reliable information about the role of …