2021 update on diffuse large B cell lymphoma: a review of current data and potential applications on risk stratification and management

S Susanibar‐Adaniya, SK Barta - American journal of …, 2021 - Wiley Online Library
Diffuse large B cell lymphoma (DLBCL), the most common type of Non‐Hodgkin lymphoma
(NHL), comprises a heterogeneous group of diseases with different biology, clinical …

Immunotherapy of neuroblastoma: facts and hopes

J Anderson, RG Majzner, PM Sondel - Clinical Cancer Research, 2022 - AACR
While the adoption of multimodal therapy including surgery, radiation, and aggressive
combination chemotherapy has improved outcomes for many children with high-risk …

T cell lymphoma and secondary primary malignancy risk after commercial CAR T cell therapy

G Ghilardi, JA Fraietta, JN Gerson, VM Van Deerlin… - Nature Medicine, 2024 - nature.com
We report a T cell lymphoma (TCL) occurring 3 months after anti-CD19 chimeric antigen
receptor (CAR) T cell immunotherapy for non-Hodgkin B cell lymphoma. The TCL was …

Dose-adjusted EPOCH-R compared with R-CHOP as frontline therapy for diffuse large B-cell lymphoma: clinical outcomes of the phase III intergroup trial alliance …

NL Bartlett, WH Wilson, SH Jung, ED Hsi… - Journal of clinical …, 2019 - ascopubs.org
PURPOSE Alliance/CALGB 50303 (NCT00118209), an intergroup, phase III study,
compared dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide …

Combination Targeted Therapy in Relapsed Diffuse Large B-Cell Lymphoma

C Melani, R Lakhotia, S Pittaluga… - … England Journal of …, 2024 - Mass Medical Soc
Background The identification of oncogenic mutations in diffuse large B-cell lymphoma
(DLBCL) has led to the development of drugs that target essential survival pathways, but …

Vincristine in combination therapy of cancer: emerging trends in clinics

J Škubník, VS Pavlíčková, T Ruml, S Rimpelová - Biology, 2021 - mdpi.com
Simple Summary Vincristine is a vinca alkaloid naturally occurring in Catharanthus roseus. It
belongs to antimitotic compounds, which arrest the cell cycle via disrupting microtubule …

[HTML][HTML] Apoptosis, necroptosis, and pyroptosis as alternative cell death pathways induced by chemotherapeutic agents?

A Gielecińska, M Kciuk, EB Yahya, T Ainane… - … et Biophysica Acta (BBA …, 2023 - Elsevier
For decades, common chemotherapeutic drugs have been established to trigger apoptosis,
the preferred immunologically “silent” form of cell death. The primary objective of this review …

[HTML][HTML] Diffuse large B-cell lymphoma (DLBCL): early patient management and emerging treatment options

P Vodicka, P Klener, M Trneny - OncoTargets and Therapy, 2022 - ncbi.nlm.nih.gov
Diffuse large B-cell lymphoma (DLBCL) represents a curable disease with a 60–70%
chance of cure with current R-CHOP chemoimmunotherapy. However, 30–40% of patients …

Challenges and opportunities in the management of diffuse large B‐cell lymphoma in older patients

M Di, SF Huntington, AJ Olszewski - The Oncologist, 2021 - academic.oup.com
Most patients with diffuse large B‐cell lymphoma (DLBCL) are diagnosed at age 60 years or
older. Challenges to effective therapy among older individuals include unfavorable biologic …

Defining and treating high-grade B-cell lymphoma, NOS

AJ Olszewski, H Kurt, AM Evens - Blood, The Journal of the …, 2022 - ashpublications.org
High-grade B-cell lymphoma (HGBL), not otherwise specified (NOS), is a recently introduced
diagnostic category for aggressive B-cell lymphomas. It includes tumors with Burkitt-like or …