Background: Type 2 diabetes mellitus (T2DM) has been associated with an increased risk of
developing several common cancers, but it is unclear whether this association is causal. We …

Background We aimed to map and describe the current state of Mendelian randomization
(MR) literature on cancer risk and to identify associations supported by robust evidence …

Background The rapid increase in the detection rate of thyroid cancer over the past few
decades has caused some unexpected economic burdens. However, that of papillary …

Context Various risk factors have been associated with the risk of thyroid cancer in
observational studies. However, the causality of the risk factors is not clear given the …

Importance Genetic and lifestyle factors are related to thyroid cancer (TC). Whether a healthy
lifestyle is associated with TC and could attenuate the influence of genetic variants in TC …

Background High-density lipoprotein cholesterol (HDL-C) plays an important role in the
reverse cholesterol transport pathway and prevents atherosclerosis-mediated disease. It has …

Obesity is associated with an increased risk of thyroid cancer, although further research is
required to understand the biological mechanisms underpinning this relationship. Reducing …

A widely discussed topic in the pathophysiology of thyroid nodules is the role of obesity, a
state that leads to increased systemic inflammatory markers. Leptin plays a vital role in …

Thyroid nodules are very common in adults. Most are benign. Of those that are malignant,
many exhibit indolent behavior. Nevertheless, familiarity with evaluation of thyroid nodules is …

Background Metabolic syndrome (MetS) has a potential connection with thyroid disease, but
its relationship with thyroid nodules (TNs) is still controversial. This study aims to clarify the …