The well-known Strecker reaction was first documented by the German chemist Adolph
Strecker (1822À1871) in 1850. 1 It was one of the earliest one-pot and atom economic …

Because of their greater stability and unique conformational properties, unnatural amino
acids are highly valued by pharmaceutical, biological, and organic chemists. This synopsis …

We report the first highly selective kinetic resolution of racemic α‐chiral azides via Cu‐
catalyzed azide‐alkyne cycloaddition (CuAAC). Newly developed pyridine‐bisoxazoline …

Catalytic enantioselective α-hydrazination of 1, 3-dicarbonyl compounds with
azodicarboxylates was investigated in the presence of our newly developed hydrogen …

Through the design and synthesis of a new chiral phosphepine, the first catalytic asymmetric
method for the [3+ 2] cycloaddition of allenes with olefins has been developed that …

Asymmetric synthesis of α‐amino acids and their phosphonate analogues has received
considerable attention due to their diverse biological activities. Quaternary α‐amino acids …

This review article provides a comprehensive update on the development of new methods
for the asymmetric synthesis of α-(trifluoromethyl)-α-amino acids, covering the literature from …

Cooperative catalysis has proven to be a particularly powerful strategy for promoting
stereoselective organic transformations under mild reaction conditions. The specific …

Abstract α, α-Disubstituted α-amino acids (α-AAs) have improved properties compared to
other types of amino acids. They serve as modifiers of peptide conformation and as …

A method is described which provides for the direct asymmetric catalytic synthesis of
trisubstituted aziridines from imines and diazo compounds. While unactivated imines were …