The upcoming 3D-printing revolution in microfluidics

N Bhattacharjee, A Urrios, S Kang, A Folch - Lab on a Chip, 2016 - pubs.rsc.org
In the last two decades, the vast majority of microfluidic systems have been built in poly
(dimethylsiloxane)(PDMS) by soft lithography, a technique based on PDMS micromolding. A …

Animal models of asthma: value, limitations and opportunities for alternative approaches

AM Holmes, R Solari, ST Holgate - Drug discovery today, 2011 - Elsevier
Asthma remains an area of considerable unmet medical need. Few new drugs have made it
to the clinic during the past 50 years, with many that perform well in preclinical animal …

[HTML][HTML] Principles for the design of multicellular engineered living systems

O Aydin, AP Passaro, R Raman, SE Spellicy… - APL …, 2022 - pubs.aip.org
Remarkable progress in bioengineering over the past two decades has enabled the
formulation of fundamental design principles for a variety of medical and non-medical …

Slip chip device and methods

RF Ismagilov, W Du, L Li, F Shen, KPF Nichols… - US Patent …, 2016 - Google Patents
A device is described having a first surface having a plurality of first areas and a second
surface having a plurality of second areas. The first surface and the second surface are …

Microfluidics: a new cosset for neurobiology

J Wang, L Ren, L Li, W Liu, J Zhou, W Yu, D Tong… - Lab on a Chip, 2009 - pubs.rsc.org
Recently, microfluidic systems have shown great potential in the study of molecular and
cellular biology. With its excellent properties, such as miniaturization, integration and …

Neuromuscular activity induces paracrine signaling and triggers axonal regrowth after injury in microfluidic lab-on-chip devices

J Sala-Jarque, F Mesquida-Veny, M Badiola-Mateos… - Cells, 2020 - mdpi.com
Peripheral nerve injuries, including motor neuron axonal injury, often lead to functional
impairments. Current therapies are mostly limited to surgical intervention after lesion, yet …

A hybrid microfluidic-vacuum device for direct interfacing with conventional cell culture methods

BG Chung, JW Park, JS Hu, C Huang, ES Monuki… - BMC …, 2007 - Springer
Background Microfluidics is an enabling technology with a number of advantages over
traditional tissue culture methods when precise control of cellular microenvironment is …

Slip chip device and methods

RF Ismagilov, W Du, L Li, F Shen, KPF Nichols… - US Patent …, 2020 - Google Patents
2016-08-02 Assigned to UNIVERSITY OF CHICAGO reassignment UNIVERSITY OF
CHICAGO ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS) …

Long-term microfluidic cultures of myotube microarrays for high-throughput focal stimulation

A Tourovskaia, X Figueroa-Masot, A Folch - Nature protocols, 2006 - nature.com
We have developed a microfluidic cell culture method that allows for the formation of linear
isolated myotubes organized in a parallel microarray. Attachment and spreading of cells are …

Spatio-temporally-complex concentration profiles using a tunable chaotic micromixer

CH Hsu, A Folch - Applied physics letters, 2006 - pubs.aip.org
The ability to present cells with stimuli that vary in space and time is key for a mechanistic
understanding of dynamic processes such as cell migration, growth, adaptation, and …