Epilepsy is a chronic disease of the central nervous system characterized by recurrent
epileptic seizures. As a result of epileptic seizure or status epilepticus oxidants are …

To valorise the bioactive constituents abundant in leaves and other parts of medicinal plants
with the objective to minimize the plant-based wastes, this study was undertaken. The main …

The brain as a target for drug delivery is a challenge in pharmaceutical research. Among the
several proposed strategies, the intranasal route represents a good strategy to deliver drugs …

Background/Aims: Ginsenoside Rb1 (Rb1) has been reported to have varieties of
neuroprotective effects. This study aimed to evaluate the effects of Rb1 on pentylenetetrazol …

Phenytoin (Dilantin) is an orally active, use-dependent voltage-gated sodium channel
inhibitor and is a potent, economical, and widely used anticonvulsant agent. The objective of …

Purpose Lamotrigine (LTG) is a broad‐spectrum antiepileptic drug that is widely used in
clinic. However, the effect of LTG on cognition and neurodegeneration during epilepsy …

Objectives: The aim of this study was to investigate dynamic thiol-disulphide homeostasis as
a novel oxidative stress parameter in patients with epilepsy. Methods: A total of 100 …

Background Epilepsy is the third most common cause of neurological disability worldwide.
Despite the introduction of antiepileptic drugs (AEDs) in the past 20 years, the seizures of …

Hyperhomocysteinemia due to cystathionine beta synthase deficiency confers diverse
clinical manifestations. It is characterized by elevated plasma homocysteine levels, a …

The current study evaluates the anticonvulsant effect low dose whole body gamma
irradiation (LDR) alone or combined with topiramate against pentylenetetrazole (PTZ) …