Synthesis and reactivity of propargylamines in organic chemistry
K Lauder, A Toscani, N Scalacci… - Chemical reviews, 2017 - ACS Publications
Propargylamines are a versatile class of compounds which find broad application in many
fields of chemistry. This review aims to describe the different strategies developed so far for …
fields of chemistry. This review aims to describe the different strategies developed so far for …
Acetylcholinesterase and carbonic anhydrase inhibitory properties of novel urea and sulfamide derivatives incorporating dopaminergic 2-aminotetralin scaffolds
In the present study a series of urea and sulfamide compounds incorporating the tetralin
scaffolds were synthesized and evaluated for their acetylcholinesterase (AChE), human …
scaffolds were synthesized and evaluated for their acetylcholinesterase (AChE), human …
Discovery of potent carbonic anhydrase and acetylcholine esterase inhibitors: Novel sulfamoylcarbamates and sulfamides derived from acetophenones
In this study, several novel sulfamides were synthesized and evaluated for their
acetylcholine esterase (AChE) and human carbonic anhydrase I, and II isoenzymes (hCA I …
acetylcholine esterase (AChE) and human carbonic anhydrase I, and II isoenzymes (hCA I …
A review towards synthesis of heterocycles using propargyl alcohols and propargyl amines
AR Pandey, DK Tiwari, A Prakhar, DP Mishra… - Monatshefte für Chemie …, 2022 - Springer
In the area of drug discovery, nitrogen/oxygen-based heterocycles have been utilized as key
intermediates and have great attention in organic chemistry. A literature survey reveals that …
intermediates and have great attention in organic chemistry. A literature survey reveals that …
The human carbonic anhydrase isoenzymes I and II (hCA I and II) inhibition effects of trimethoxyindane derivatives
Abstract Carbonic anhydrases (CAs, EC 4.2. 1.1) had six genetically distinct families
described to date in various organisms. There are 16 known CA isoforms in humans. Human …
described to date in various organisms. There are 16 known CA isoforms in humans. Human …
Acetylcholinesterase inhibitory and antioxidant activities of novel symmetric sulfamides derived from phenethylamines
The antioxidant and acetylcholinesterase inhibitory properties of novel symmetric sulfamides
derived from phenethylamines were evaluated. Phenethylamines 8–11 were reacted with …
derived from phenethylamines were evaluated. Phenethylamines 8–11 were reacted with …
Synthesis and inhibitory properties of some carbamates on carbonic anhydrase and acetylcholine esterase
A series of carbamate derivatives were synthesized and their carbonic anhydrase I and II
isoenzymes and acetylcholinesterase enzyme (AChE) inhibitory effects were investigated …
isoenzymes and acetylcholinesterase enzyme (AChE) inhibitory effects were investigated …
Design, synthesis and anticholinergic properties of novel α-benzyl dopamine, tyramine, and phenethylamine derivatives
A Naderi, A Akıncıoğlu, A Çağan, H Çelikkaleli… - Bioorganic …, 2024 - Elsevier
Due to the important biological properties of dopamine, phenethylamine, and tyramine
derivatives in the central nervous system, herein the synthesis of novel α-benzyl dopamine …
derivatives in the central nervous system, herein the synthesis of novel α-benzyl dopamine …
Synthesis and anticancer activity of novel ureas and sulfamides incorporating 1-aminotetralins
Background and Aims In the present study, a series of ureas and sulfamides derived from 1-
aminotetralins were synthesized. For this purpose, urea and sulfamide analogues were …
aminotetralins were synthesized. For this purpose, urea and sulfamide analogues were …
Synthesis of propargylamine: pioneering a green path with non-conventional KA2 coupling approach
L Khadanga, SM Roopan - Molecular Diversity, 2024 - Springer
The KA 2 coupling reaction is a well-explored and versatile method for forming C–C bonds
in synthetic chemistry. It is composed of ketone, amine, and alkyne, which play a major role …
in synthetic chemistry. It is composed of ketone, amine, and alkyne, which play a major role …