Ion channels in gliomas—from molecular basis to treatment

AF Elias, BC Lin, BJ Piggott - International Journal of Molecular Sciences, 2023 - mdpi.com
Ion channels provide the basis for the nervous system's intrinsic electrical activity. Neuronal
excitability is a characteristic property of neurons and is critical for all functions of the …

Potassium channels, glucose metabolism and glycosylation in cancer cells

A Wawrzkiewicz-Jałowiecka, A Lalik… - International Journal of …, 2023 - mdpi.com
Potassium channels emerge as one of the crucial groups of proteins that shape the biology
of cancer cells. Their involvement in processes like cell growth, migration, or electric …

[HTML][HTML] mitoBKCa is functionally expressed in murine and human breast cancer cells and promotes metabolic reprogramming

H Bischof, S Maier, P Koprowski, B Kulawiak… - eLife, 2023 - elifesciences.org
Alterations in the function of K+ channels such as the voltage-and Ca2+ activated K+
channel of large conductance (BKCa) reportedly promote breast cancer (BC) development …

IKCa channels control breast cancer metabolism including AMPK-driven autophagy

D Gross, H Bischof, S Maier, K Sporbeck… - Cell Death & …, 2022 - nature.com
Abstract Ca2+-activated K+ channels of intermediate conductance (IK) are frequently
overexpressed in breast cancer (BC) cells, while IK channel depletion reduces BC cell …

XNA probe and CRISPR/Cas12a-powered flexible fluorescent and electrochemical dual-mode biosensor for sensitive detection of m6A site-specific RNA modification

Q Pu, Y Ye, J Hu, C Xie, X Zhou, H Yu, F Liao, S Jiang… - Talanta, 2023 - Elsevier
Abstract N6-methyladenosine (m6A) in RNAs is closely related to various biological
progresses, but the specific regulatory mechanisms are still unclear. The existing m6A single …

Mitochondria-Targeted Ratiometric KLA-Tweezers for Fluorescence Imaging of Potassium Ions

N Zhang, H Cheng, Y Liu - Analytical Chemistry, 2024 - ACS Publications
Intracellular potassium ions play a crucial role in cellular homeostasis associated with
physiological and pathological processes. It is still challenging but definitely crucial to …

Regulation of ion permeation of the KcsA channel by applied midinfrared field

Y Wang, H Wang, W Ding, X Zhao, Y Li… - International Journal of …, 2022 - mdpi.com
Ion transport molecules are involved in many physiological and pathological processes and
are considered potential targets for cancer treatment. In the large family of ion transport …

mitoBKCa is functionally expressed in murine and human breast cancer cells and potentially contributes to metabolic reprogramming

H Bischof, S Maier, P Koprowski, B Kulawiak… - Elife, 2024 - elifesciences.org
Alterations in the function of K+ channels such as the voltage-and Ca 2+-activated K+
channel of large conductance (BK Ca) reportedly promote breast cancer (BC) development …

mitoBKCa is functionally expressed in murine and human breast cancer cells and potentially contributes to metabolic reprogramming

B Helmut, S Maier, K Piotr, K Bogusz, S Burgstaller… - eLife, 2024 - search.proquest.com
Alterations in the function of K+ channels such as the voltage-and Ca 2+-activated K+
channel of large conductance (BK Ca) reportedly promote breast cancer (BC) development …

Review on Lysosomal Metal Ion Detection Using Fluorescent Probes

A Silswal, KP, AL Koner - ACS omega, 2024 - ACS Publications
Metal ions are indispensable and play an important role in living systems. Metal ions
coordinated to metalloenzymes pocket activate the bound substrate and labile metal ions …