Autophagy is a genetically well-controlled cellular process that is tightly controlled by a set of
core genes, including the family of autophagy-related genes (ATG). Autophagy is a “double …

Autophagy is a ubiquitous cellular process that regulates cell growth, survival, development
and death. Its process is closely associated with diverse conditions, such as liver diseases …

Peroxisome proliferator-activated receptor (PPAR) γ is a global transcriptional regulator
associated with anti-inflammatory actions. It is highly expressed in alveolar macrophages …

Autophagy is a degradative pathway that plays an essential role in maintaining cellular
homeostasis. Most early studies of autophagy focused on its involvement in age-associated …

Innate and adaptive immune responses against pathogens are known to be carefully
orchestrated by specific cytokines that initiate and down regulate immune cell functions from …

Background: Metabolic pathways perturbations lead to skeletal muscular atrophy in the
cachexia and sarcopenia due to increased catabolism. Pro-inflammatory cytokines induce …

To survive and replicate in macrophages Mycobacterium tuberculosis (Mtb) has developed
strategies to subvert host defence mechanisms, including autophagy. Autophagy induction …

Leprosy is a chronic infectious disease that may present different clinical forms according to
the immune response of the host. Levels of IFN-γ are significantly raised in paucibacillary …

Abstract Interleukin-27 (IL-27) is a cytokine that suppresses human immunodeficiency virus
(HIV)-1 infection in macrophages and is considered as an immunotherapeutic reagent for …

Over the years, interleukin (IL)-27 has received much attention because of its highly
divergent, sometimes even opposing, functions in immunity. IL-30, the p28 subunit that forms …