It is not often realized that the absolute protein specificity is an exception rather than a rule.
Two major kinds of protein multi-specificities are promiscuity and moonlighting. This review …

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a glycolytic enzyme whose role in
cell metabolism and homeostasis is well defined, while its function in pathologic processes …

The pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection involves dysregulations of iron metabolism, and although the mechanism of this …

Abstract Mycobacterium tuberculosis (M. tb), the major causative agent of tuberculosis, has
evolved mechanisms to evade host defenses and persist within host cells. Host-directed …

Abstract Ethnopharmacological relevance Niujiaodihuang Detoxify Decoction (NDD) is an
integrated traditional Chinese medicine prescription that has been used as a therapeutic …

Differences in individual host responses have emerged as an issue regarding the health
benefits of probiotics. Here, we applied ribosome engineering (RE) technology, developed …

Introduction: Coronavirus disease 2019 caused by coronavirus-2 (SARS-CoV-2) has
emerged as an aggressive viral pandemic. Health care providers confront a challenging task …

Homeostasis is a self-regulatory dynamic process that maintains a stable internal
environment in the human body. These regulations are essential for the optimal functioning …

Chronic myeloid leukemia is a hematological cancer, where disease relapse and drug
resistance are caused by bone-hosted-residual leukemia cells. An innovative resolution is …

Introduction Although morphological and anatomical studies indicate that venous wall
weakening and subendothelial fibrosis characterize varicose veins (VV), the pathogenesis …