The 2022 World Health Organization classification of tumors of the urinary system and male genital organs—part B: prostate and urinary tract tumors

GJ Netto, MB Amin, DM Berney, EM Compérat, AJ Gill… - European urology, 2022 - Elsevier
Abstract The 2022 World Health Organization (WHO) classification of the urinary and male
genital tumors was recently published by the International Agency for Research on Cancer …

Immune checkpoint inhibitors for the treatment of bladder cancer

A Lopez-Beltran, A Cimadamore, A Blanca, F Massari… - Cancers, 2021 - mdpi.com
Simple Summary In this review, we examined relevant clinical trial results with immune
checkpoint inhibitors in patients with metastatic urothelial cancer. We also focused on the …

Programmed death ligand-1 (PD-L1) as a predictive marker for immunotherapy in solid tumours: a guide to immunohistochemistry implementation and interpretation

EC Paver, WA Cooper, AJ Colebatch, PM Ferguson… - Pathology, 2021 - Elsevier
Immunotherapy with checkpoint inhibitors is well established as an effective treatment for
non-small cell lung cancer and melanoma. The list of approved indications for treatment with …

[HTML][HTML] PD-L1 assessment in urothelial carcinoma: a practical approach

M Eckstein, A Cimadamore, A Hartmann… - Annals of …, 2019 - ncbi.nlm.nih.gov
Abstract Five programmed death-1 (PD-1)/programmed death-ligand 1 (PD-L1) inhibitors
are currently approved for treatment of locally advanced or metastatic urothelial carcinoma …

Prognostic impact of variant histologies in urothelial bladder cancer treated with radical cystectomy

F Claps, MW van de Kamp, R Mayr… - BJU …, 2023 - Wiley Online Library
Objectives To evaluate variant histologies (VHs) for disease‐specific survival (DSS) in
patients with invasive urothelial bladder cancer (BCa) undergoing radical cystectomy (RC) …

Molecular pathology of urothelial carcinoma

A Lopez-Beltran, A Cimadamore, R Montironi, L Cheng - Human pathology, 2021 - Elsevier
The current personalized oncology era has witnessed significant efforts to integrate clinical,
pathological, and molecular classifications. The growing need for molecular biomarkers to …

The genitourinary pathology society update on classification of variant histologies, T1 substaging, molecular taxonomy, and immunotherapy and PD-L1 testing …

E Compérat, MB Amin, JI Epstein… - Advances in anatomic …, 2021 - journals.lww.com
Abstract The Genitourinary Pathology Society (GUPS) undertook a critical review of the
recent advances in bladder cancer focusing on important topics of high interest for the …

Expression of four cancer-testis antigens in TNBC indicating potential universal immunotherapeutic targets

J Xiao, F Huang, L Li, L Zhang, L Xie, B Liu - Journal of Cancer Research …, 2023 - Springer
Objective Immunotherapy is an attractive treatment for breast cancer. Cancer-testis antigens
(CTAs) are potential targets for immunotherapy for their restricted expression. Here, we …

Evaluation of therapeutic targets in histological subtypes of bladder cancer

S Wucherpfennig, M Rose, A Maurer… - International journal of …, 2021 - mdpi.com
Histologically, bladder cancer is a heterogeneous group comprising urothelial carcinoma
(UC), squamous cell carcinoma, adenocarcinomas (ACs), urachal carcinomas (UrCs), and …

PD-L1 expression in head and neck cancer tissue specimens decreases with time

G Karpathiou, M Vincent, JM Dumollard… - … -Research and Practice, 2022 - Elsevier
Background PD-L1 immunohistochemical expression is used as an important theranostic
marker in various malignancies, including head and neck squamous cell carcinoma …