The development of chloroquine as an antimalarial drug and the subsequent evolution of
drug-resistant Plasmodium strains had major impacts on global public health in the 20th …

Quinoline-containing antimalarial drugs, such as chloroquine, quinine and mefloquine, are
mainstays of chemotherapy against malaria. The molecular basis of the action of these …

Continued and sustainable improvements in antimalarial medicines through focused
research and development are essential for the world's future ability to treat and control …

New drugs against malaria are greatly needed. Many approaches to antimalarial drug
discovery are available. These approaches must take into account specific concerns, in …

Background: The emergence and spread of Plasmodium berghei with resistance to
chloroquine (CQ), the safest and cheapest antimalarial drug coupled with the increasing …

The prevention and treatment of malaria is heavily dependent on antimalarial drugs.
However, beginning with the emergence of chloroquine (CQ)-resistant Plasmodium …

Background The initial global outbreak of the novel coronavirus disease 2019 (COVID-
2019) pandemic, which is responsible for the severe acute respiratory syndrome 2 (SARS …

Publisher Summary This chapter defines drug resistance as “the ability of a parasite to
survive in the presence of concentrations of a drug that normally destroy parasites of the …

H1-receptor antagonists are widely used in the treatment of allergic disorders in children.
The evidence base for their use is strongest in allergic rhinoconjunctivitis (1)(Table 1). Most …

■ Summary Drugs with antihistamine action are among the most commonly prescribed
medicines in pediatrics. According to the International Medical Statistics (IMS), almost two …