Intron retention is a robust marker of intertumoral heterogeneity in pancreatic ductal adenocarcinoma

DJ Tan, M Mitra, AM Chiu, HA Coller - NPJ genomic medicine, 2020 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with a 5-year survival
rate of< 8%. Unsupervised clustering of 76 PDAC patients based on intron retention (IR) …

The identification of protein and RNA interactors of the splicing factor Caper in the adult Drosophila nervous system

MB Titus, AW Chang, N Popitsch… - Frontiers in Molecular …, 2023 - frontiersin.org
Post-transcriptional gene regulation is a fundamental mechanism that helps regulate the
development and healthy aging of the nervous system. Mutations that disrupt the function of …

A comparison of low read depth QuantSeq 3′ sequencing to total RNA-Seq in FUS mutant mice

S Jarvis, N Birsa, M Secrier, P Fratta, V Plagnol - Frontiers in Genetics, 2020 - frontiersin.org
Transcriptomics is a developing field with new methods of analysis being produced which
may hold advantages in price, accuracy, or information output. QuantSeq is a form of 3 …

Low level of expression of C-terminally truncated human FUS causes extensive changes in the spinal cord transcriptome of asymptomatic transgenic mice

EA Lysikova, S Funikov, AP Rezvykh… - Neurochemical …, 2020 - Springer
A number of mutations in a gene encoding RNA-binding protein FUS have been linked to
the development of a familial form of amyotrophic lateral sclerosis known as FUS-ALS. C …

[PDF][PDF] Intron retention is a robust marker of intertumoral heterogeneity in pancreatic ductal

DJ Tan, M Mitra, AM Chiu - NPJ genomic medicine, 5 (1), 2020 - scholar.archive.org
Cancer of the pancreas is the fourth most common cause of cancer deaths for men and
women in the United States 1 with an estimated 57,600 new cases in 2020 and 47,050 …

Gene therapy vectors

ET Wang, JA Berglund, E Delgado… - US Patent App. 17 …, 2022 - Google Patents
2022-07-21 Assigned to UNIVERSITY OF FLORIDA RESEARCH FOUNDATION,
INCORPORATED reassignment UNIVERSITY OF FLORIDA RESEARCH FOUNDATION …

[PDF][PDF] НОВАЯ МОДЕЛЬ ФРОНТО-ТЕМПОРАЛЬНОЙ ДЕМЕНЦИИ НА ТРАНСГЕННЫХ МЫШАХ С МЕДЛЕННО ПРОГРЕССИРУЮЩЕЙ FUS-ПРОТЕИНОПАТИЕЙ

ЕА Лысикова - ndp.ipac.ac.ru
Защита состоится «___» _________ 2020 года в _____часов на заседании
диссертационного совета Д001. 003.01 при ФГБНУ «Научно-исследовательский …

Discovery of cancer splicing and associated auto-regulatory networks through cross-species circadian analysis

K Ramasamy - 2019 - search.proquest.com
Disruption of circadian rhythm can lead to serious sleeping disorders and predispose to a
number of life-threatening diseases, including cancer. Circadian splicing adds an additional …

[引用][C] Investigating high dimensional alternative splicing during haematopoiesis

K Tiwari - 2021 - espace.library.uq.edu.au
The haematopoietic system is responsible for the daily turnover of trillions of blood cells in a
human adult. It relies on the maintenance of a cellular hierarchy, ie, a select few …