The NF-κB (nuclear factor κ-light-chain-enhancer of activated B cells) transcription factor
family is a pleiotropic regulator of many cellular signaling pathways, providing a mechanism …

Obesity is an alarming disease that favors the upset of other illnesses and enhances
mortality. It is spreading fast worldwide may affect more than 1 billion people by 2030. The …

BACKGROUND Gastric injury is the most common digestive system disease worldwide and
involves inflammation, which can lead to gastric ulcer or gastric cancer (GC). Matrix …

Inflammatory Bowel Diseases (IBD) are difficult to model as freshly acquired tissues are
short-lived, provide data as a snapshot in time, and are not always accessible. Many …

Cancer is a major global health problem and the second leading cause of death worldwide.
When detected early, surgery provides a potentially curative intervention for many solid …

Atherosclerosis is an arterial inflammatory disease. The circulating level of the CC
chemokine ligand (CCL4) is increased in atherosclerotic patients. This study aimed to …

Tendon injuries occur commonly in both human and equine athletes, and poor tendon
regeneration leads to functionally deficient scar tissue and an increased frequency of re …

Thromboangiitis obliterans (TAO)(also known as Buerger's disease) is an inflammatory
vascular disease that predominantly affects small-and medium-sized blood vessels of …

Background Tumor necrosis factor-α (TNF-α) is a proinflammatory cytokine and elevated in
the regions of tissue injury and inflammatory diseases. The deleterious effects of TNF-α on …

Over the past two decades biologic therapies have seen a rapid uptake in the management
of ocular inflammation. Peripheral ulcerative keratitis (PUK), once a harbinger of blindness …