A review of vulnerability and risks for schizophrenia: Beyond the two hit hypothesis
Schizophrenia risk has often been conceptualized using a model which requires two hits in
order to generate the clinical phenotype—the first as an early priming in a genetically …
order to generate the clinical phenotype—the first as an early priming in a genetically …
The neural diathesis-stress model of schizophrenia revisited: An update on recent findings considering illness stage and neurobiological and methodological …
Over the past decade, our understanding of the role of stress in serious mental illness has
become more sophisticated. In this paper, we revisit the neural diathesis-stress model of …
become more sophisticated. In this paper, we revisit the neural diathesis-stress model of …
Maternal immune activation: reporting guidelines to improve the rigor, reproducibility, and transparency of the model
Abstract The 2017 American College of Neuropychopharmacology (ACNP) conference
hosted a Study Group on 4 December 2017, Establishing best practice guidelines to …
hosted a Study Group on 4 December 2017, Establishing best practice guidelines to …
The immune system and developmental programming of brain and behavior
SD Bilbo, JM Schwarz - Frontiers in neuroendocrinology, 2012 - Elsevier
The brain, endocrine, and immune systems are inextricably linked. Immune molecules have
a powerful impact on neuroendocrine function, including hormone–behavior interactions …
a powerful impact on neuroendocrine function, including hormone–behavior interactions …
Accelerated brain aging in schizophrenia and beyond: a neuroanatomical marker of psychiatric disorders
Structural brain abnormalities are central to schizophrenia (SZ), but it remains unknown
whether they are linked to dysmaturational processes crossing diagnostic boundaries …
whether they are linked to dysmaturational processes crossing diagnostic boundaries …
Glutamate in Schizophrenia: A Focused Review and Meta-Analysis of 1H-MRS Studies
A Marsman, MP Van Den Heuvel… - Schizophrenia …, 2013 - academic.oup.com
Schizophrenia is a severe chronic psychiatric illness, characterized by hallucinations and
delusions. Decreased brain volumes have been observed in the disease, although the …
delusions. Decreased brain volumes have been observed in the disease, although the …
Early-life programming of later-life brain and behavior: a critical role for the immune system
SD Bilbo, JM Schwarz - Frontiers in behavioral neuroscience, 2009 - frontiersin.org
The immune system is well characterized for its critical role in host defense. Far beyond this
limited role however, there is mounting evidence for the vital role the immune system plays …
limited role however, there is mounting evidence for the vital role the immune system plays …
Microglial activation and progressive brain changes in schizophrenia
LE Laskaris, MA Di Biase, I Everall… - British journal of …, 2016 - Wiley Online Library
Schizophrenia is a debilitating disorder that typically begins in adolescence and is
characterized by perceptual abnormalities, delusions, cognitive and behavioural …
characterized by perceptual abnormalities, delusions, cognitive and behavioural …
Age of onset of schizophrenia: perspectives from structural neuroimaging studies
Many of the major neuropsychiatric illnesses, including schizophrenia, have a typical age of
onset in late adolescence. Late adolescence may reflect a critical period in brain …
onset in late adolescence. Late adolescence may reflect a critical period in brain …
Structural brain imaging evidence for multiple pathological processes at different stages of brain development in schizophrenia
The underlying neurobiology of emerging psychotic disorders is not well understood. While
there is evidence from structural imaging and other studies supporting the popular notion …
there is evidence from structural imaging and other studies supporting the popular notion …