Classically, the CNS is described as displaying immune privilege, as it shows attenuated
responses to challenge by alloantigen. However, the CNS does show local inflammation in …

Climate change is a worldwide challenge. Its consequences do encompass severe threats
not only for the existence and somatic health, but also for the mental health of children and …

ZIKA virus (ZIKV) is an emerging pathogen responsible for neurological disorders and
congenital microcephaly. However, the molecular basis for ZIKV neurotropism remains …

The re-emergence of Zika virus (ZIKV), a mosquito-borne and sexually transmitted flavivirus
circulating in> 70 countries and territories, poses a significant global threat to public health …

Neurological disorders have emerged as a predominant healthcare concern in recent years
due to their severe consequences on quality of life and prevalence throughout the world …

Initial reports of congenital Zika virus (ZIKV) infection focused on microcephaly at birth with
severe brain anomalies; the phenotype has broadened to include microcephaly that …

Infections during pregnancy can seriously damage fetal neurodevelopment by aberrantly
activating the maternal immune system, directly impacting fetal neural cells. Increasing …

Human infection by different flaviviruses may cause severe neurologic syndromes, through
pathogenic mechanisms that are still largely unknown. Japanese encephalitis virus (JEV) …

Microglia cells are the unique residential macrophages of the central nervous system (CNS).
They have a special origin, as they derive from the embryonic yolk sac and enter the …

Maternal viral infection and immune response are known to increase the risk of altered
development of the foetal brain. Given the ongoing global pandemic of coronavirus disease …