Macrophages and microglia: the cerberus of glioblastoma

A Buonfiglioli, D Hambardzumyan - Acta neuropathologica …, 2021 - Springer
Glioblastoma (GBM) is the most aggressive and deadliest of the primary brain tumors,
characterized by malignant growth, invasion into the brain parenchyma, and resistance to …

Conventional MRI evaluation of gliomas

N Upadhyay, AD Waldman - The British journal of radiology, 2011 - academic.oup.com
MRI using T 1 weighted, T2 weighted and gadolinium-enhanced sequences plays a central
clinical role in diagnosis, characterisation, surveillance and therapeutic monitoring of …

Radiomic features from the peritumoral brain parenchyma on treatment-naive multi-parametric MR imaging predict long versus short-term survival in glioblastoma …

P Prasanna, J Patel, S Partovi, A Madabhushi… - European …, 2017 - Springer
Objective Despite 90% of glioblastoma (GBM) recurrences occurring in the peritumoral brain
zone (PBZ), its contribution in patient survival is poorly understood. The current study …

Radiogenomics of glioblastoma: machine learning–based classification of molecular characteristics by using multiparametric and multiregional MR imaging features

P Kickingereder, D Bonekamp, M Nowosielski, A Kratz… - Radiology, 2016 - pubs.rsna.org
Purpose To evaluate the association of multiparametric and multiregional magnetic
resonance (MR) imaging features with key molecular characteristics in patients with newly …

Identification of noninvasive imaging surrogates for brain tumor gene-expression modules

M Diehn, C Nardini, DS Wang… - Proceedings of the …, 2008 - National Acad Sciences
Glioblastoma multiforme (GBM) is the most common and lethal primary brain tumor in adults.
We combined neuroimaging and DNA microarray analysis to create a multidimensional map …

Relationship between tumor enhancement, edema, IDH1 mutational status, MGMT promoter methylation, and survival in glioblastoma

JA Carrillo, A Lai, PL Nghiemphu… - American Journal …, 2012 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Both IDH1 mutation and MGMT promoter methylation are
associated with longer survival. We investigated the ability of imaging correlates to serve as …

Radiogenomic analysis of oncological data: a technical survey

M Incoronato, M Aiello, T Infante, C Cavaliere… - International journal of …, 2017 - mdpi.com
In the last few years, biomedical research has been boosted by the technological
development of analytical instrumentation generating a large volume of data. Such …

The basic characteristics of the pentraxin family and their functions in tumor progression

Z Wang, X Wang, H Zou, Z Dai, S Feng… - Frontiers in …, 2020 - frontiersin.org
The pentraxin is a superfamily of proteins with the same domain known as the pentraxin
domain at C-terminal. This family has two subgroups, namely; short pentraxins (C-reactive …

Radiogenomic analysis of hypoxia pathway is predictive of overall survival in Glioblastoma

N Beig, J Patel, P Prasanna, V Hill, A Gupta… - Scientific reports, 2018 - nature.com
Hypoxia, a characteristic trait of Glioblastoma (GBM), is known to cause resistance to chemo-
radiation treatment and is linked with poor survival. There is hence an urgent need to non …

Apparent diffusion coefficient histogram analysis stratifies progression-free survival in newly diagnosed bevacizumab-treated glioblastoma

WB Pope, A Lai, R Mehta, HJ Kim… - American Journal …, 2011 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Currently it is difficult to predict tumor response to anti-
angiogenic therapy in individual patients. Our aim was to determine if ADC histogram …