Finding novel pharmaceuticals in the systems biology era using multiple effective drug targets, phenotypic screening and knowledge of transporters: where drug …

DB Kell - The FEBS Journal, 2013 - Wiley Online Library
Despite the sequencing of the human genome, the rate of innovative and successful drug
discovery in the pharmaceutical industry has continued to decrease. Leaving aside …

Metabolic engineering of Clostridium acetobutylicum for enhanced production of butyric acid

YS Jang, HM Woo, JA Im, IH Kim, SY Lee - Applied microbiology and …, 2013 - Springer
Clostridium acetobutylicum has been considered as an attractive platform host for
biorefinery due to its metabolic diversity. Considering its capability to overproduce butanol …