Abstract The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …

Vaccines and monoclonal antibody treatments to prevent severe coronavirus disease 2019
(COVID-19) illness were available within a year of the pandemic being declared but there …

The worldwide outbreak of COVID-19 caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has become a global pandemic. Alongside vaccines, antiviral …

The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in an unprecedented setback …

SARS-CoV-2 proteases Mpro and PLpro are promising targets for antiviral drug
development. In this study, we present an antiviral screening strategy involving a novel in …

SARS-CoV-2 lineages have diverged into highly prevalent variants termed" variants of
concern"(VOCs). Here, we characterized emerging SARS-CoV-2 spike polymorphisms in …

Abstract The BioGRID (Biological General Repository for Interaction Datasets, thebiogrid.
org) is an open‐access database resource that houses manually curated protein and …

The SARS-CoV-2 virus has infected more than 261 million people and has led to more than
5 million deaths in the past year and a half (https://www. who. org/). Individuals with SARS …

To better understand host-virus genetic dependencies and find potential therapeutic targets
for COVID-19, we performed a genome-scale CRISPR loss-of-function screen to identify …

There is an urgent need for antiviral agents that treat severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection. We screened a library of 1900 clinically safe drugs …