I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

Chronic rhinosinusitis (CRS) is a sino-nasal chronic inflammatory disease, occurring in 5–
15% of the general population. CRS with nasal polyps (CRSwNP) is present in up to 30% of …

Background Central compartment atopic disease (CCAD) is a recently described variant of
chronic rhinosinusitis with nasal polyp (CRSwNP) associated with inhalant allergy. An …

Background Atopy has a strong association with chronic rhinosinusitis (CRS). Objective To
understand whether patients with atopy and CRS can be defined by markers of tissue …

Purpose The allergic phenotype of chronic rhinosinusitis (CRS) and central compartment
atopic disease (CCAD) have been described. The CCAD is a radiological phenotype in …

Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a distinct inflammatory
disease of the upper airways with a significant impact on the health and quality of life of …

Background: Global airway disease, with symptoms from both upper and lower airways, is a
challenging problem for clinicians. Our goal is to design one single standard test for the …

Background Endoscopic vidian neurectomy is expected to provide good therapeutic relief in
patients with allergic rhinitis (AR) being refractory to medication therapy or conservative …

Introduction Central compartment atopic disease (CCAD) is a newly recognized variant
subtype of chronic rhinosinusitis (CRS). Although CCAD has been reported to be correlated …

Background Allergic rhinitis (AR) and nonallergic rhinitis (NAR) often are comorbid with
chronic rhinosinusitis (CRS). Finding a convenient test that distinguishes these complex …