The animal model deals with the species other than the human, as it can imitate the disease
progression, its' diagnosis as well as a treatment similar to human. Discovery of a drug …

Rapid developments in Regenerative Medicine and Tissue Engineering has witnessed an
increasing drive toward clinical translation of breakthrough technologies. However, the …

Once damaged, articular cartilage has a limited potential to repair. Clinically, a repair tissue
is formed, yet, it is often mechanically inferior fibrocartilage. The use of monolayer expanded …

Cell-laden hydrogels are the primary building blocks for bioprinting, and, also termed
bioinks, are the foundations for creating structures that can potentially recapitulate the …

Simple Summary We review the value of large animal models for improving the translation of
biomedical research for human application, focusing primarily on sheep. Abstract An …

Multi-material 3D printing technologies that resolve features at different lengths down to the
microscale open new avenues for regenerative medicine, particularly in the engineering of …

To diminish the learning curve associated with using swine as models, Swine in the
Laboratory: Surgery, Anesthesia, Imaging, and Experimental Techniques, Second Edition …

Much research is currently ongoing into new therapies for cartilage defect repair with new
biomaterials frequently appearing which purport to have significant regenerative capacity …

Articular cartilage is integral to the mechanical function of many joints in the body. When
injured, cartilage lacks the capacity to self-heal, and thus, therapies and replacements have …

Long-term clinical repair of articular cartilage remains elusive despite advances in cartilage
tissue engineering. Only one cartilage repair therapy classified as a “cellular and gene …