Phoneutria nigriventer venom (PNV) is a complex mixture of toxins exerting multiple
pharmacological effects that ultimately result in severe local pain at the site of the bite. It has …

Mast cells (MCs) are immune cells and are widely distributed throughout the body. MCs are
not only classically viewed as effector cells of some allergic diseases but also participate in …

Humankind has always been fascinated by venomous animals, as their toxic substances
have transformed them into symbols of power and mystery. Over the centuries, researchers …

The onset, progression, and severity of pain following rattlesnake envenomation are highly
variable between patients. Pain can be severe and persistent, seemingly refractory to opioid …

The management of pain is a world health issue. Available painkillers induce undesired side
effects and are sometimes inefficient. Spirulina biomass has promoted anti-inflammatory …

Background The diversity of components in arthropod venoms constitute a rich source of
bioactive molecules. Brazil is the most biodiverse country in the world, comprising 15 to 20 …

Ao longo de bilhões de anos de evolução da vida na Terra, os animais desenvolveram
características bastante engenhosas que auxiliam na obtenção de alimento. Alguns …