[HTML][HTML] Identification of two pIgR-like molecules in teleost fish with opposite roles in mucosal immunity against bacterial infection

H Xu, Z Wang, Z Huang, X Chen, R Lin, Y Yu… - Water Biology and …, 2023 - Elsevier
Polymeric immunoglobulin (Ig) receptor-like (pIgRL) molecules have been identified in
teleost fish. However, compared to functional studies of their related genes (eg, mammalian …

Micro-and nano-plastics induce kidney damage and suppression of innate immune function in zebrafish (Danio rerio) larvae

H Yang, J Ju, Y Wang, Z Zhu, W Lu, Y Zhang - Science of The Total …, 2024 - Elsevier
Aquatic environments serve as critical repositories for pollutants and have significantly
accumulated micro-and nanoplastics (MNPs) due to the extensive production and …

Multiomics analysis revealed miRNAs as potential regulators of the immune response in Carassius auratus gills to Aeromonas hydrophila infection

J Huo, X Hu, J Bai, A Lv - Frontiers in Immunology, 2023 - frontiersin.org
The gill of fish is an important immune organ for pathogen defense, but its microRNA
(miRNA) expression and regulatory mechanism remain unclear. In this study, we report on …

Molecular insight into regulation of miRNAs in the spleen of zebrafish (Danio rerio) upon pathogenic Streptococcus parauberis infection

TD Liyanage, C Nikapitiya, J Lee… - Fish & Shellfish …, 2020 - Elsevier
MicroRNAs (miRNAs) constitute a group of small non-coding RNAs (~ 22 nucleotides) and
one of their main functions is to regulate the immune responses. Gram-positive bacterium …

Characterization of the MMP9 Gene and Its Association with Cryptocaryon irritans Resistance Traits in Trachinotus ovatus (Linnaeus, 1758)

J Liu, KC Zhu, JM Pan, HY Guo, BS Liu, N Zhang… - Genes, 2023 - mdpi.com
The MMPs are endogenous proteolytic enzymes that require zinc and calcium as cofactors.
MMP9 is one of the most complex matrix metalloproteinases in the gelatinase family and has …

[HTML][HTML] Metabolomic and transcriptomic profiles after immune stimulation in the zebrafish testes

TA van Gelderen, C Ladisa, M Salazar-Moscoso… - Genomics, 2023 - Elsevier
Fish farms are prone to disease outbreaks and stress due to high-density rearing conditions
in tanks and sea cages, adversely affecting growth, reproduction, and metabolism. To …

Lipopolysaccharide-induced TNFα factor (LITAF) promotes inflammatory responses and activates apoptosis in zebrafish Danio rerio

K Chen, J Tian, J Wang, Z Jia, Q Zhang, W Huang… - Gene, 2021 - Elsevier
Lipopolysaccharide-induced TNFα factor (LITAF) is an important transcription factor which
activates the transcription of TNFα and regulates cell apoptosis and inflammatory response …

Integrated time-series biochemical, transcriptomic, and metabolomic analyses reveal key metabolites and signaling pathways in the liver of the Chinese soft-shelled …

L Ji, C Chen, J Zhu, X Hong, X Liu, C Wei… - Frontiers in …, 2024 - frontiersin.org
Introduction Aeromonas hydrophila, a bacterium widely distributed in the natural
environment, causes multiple diseases in various animals. Exploring the mechanism of the …

Identification of two interleukin 17 receptor C (IL-17RC) genes and their binding activities to three IL-17A/F ligands in the Japanese medaka, Oryzias latipes

N Harada, Y Okamura, T Kono, M Sakai… - Developmental & …, 2021 - Elsevier
Abstract In mammals, interleukin (IL)-17 receptor C (IL-17RC) and IL-17RA mediate IL-17A
and IL-17F signaling to produce mucin, antimicrobial peptides, and maintain healthy …

SIGIRR plays a dual role in zebrafish infected with Edwardsiella piscicida: boosting digestive system wellness and mitigating inflammation

T Yu, S Yang, L Zhang, D Deng, X Zhang, K Luo… - Fish & Shellfish …, 2024 - Elsevier
Single immunoglobulin interleukin-1 receptor-associated protein (SIGIRR) negatively
regulates the inflammatory response induced by bacterial infection by inhibiting the …