Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is
released by various cell types and is an attractive biomarker of inflammation, ischemia …

Chronic (neuro) inflammation plays an important role in many age-related central nervous
system (CNS) diseases, including Alzheimer's disease, Parkinson's disease and vascular …

In dry age-related macular degeneration (AMD), LCN2 (lipocalin 2) is upregulated. Whereas
LCN2 has been implicated in AMD pathogenesis, the mechanism remains unknown. Here …

Lipocalin 2 (Lcn2), an innate immune protein, has emerged as a critical iron regulatory
protein during physiological and inflammatory conditions. As a bacteriostatic factor, Lcn2 …

Abstract Trastuzumab-emtansine (T-DM1) is an antibody–drug conjugate (ADC) that was
approved recently to treat HER2+ breast cancers. Despite its impressive clinical efficacy in …

Here we report on the design, synthesis, and assembly of an enzymatic programmable
peptide system inspired by endocytic processes to induce molecular assemblies formation …

Lipocalin 2 (LCN2) is a secreted protein that belongs to the Lipocalins, a group of
transporters of small lipophilic molecules such as steroids, lipopolysaccharides, iron, and …

Background and aims Obesity is a state of chronic low-grade systemic inflammation. Recent
studies showed that NLRP3 inflammasome initiates metabolic dysregulation in adipose …

Iron overload is associated with various pathological changes which contribute to heart
failure. Here, we examined mechanisms via which iron alters cardiomyocyte insulin …

Environmental insults such as oxidative stress can damage cell membranes. Lysosomes are
particularly sensitive to membrane permeabilization since their function depends on …