Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …

Cancer is one of the leading causes of human death worldwide. Treatment of cancer
exhausts significant medical resources, and the morbidity and mortality caused by cancer is …

RNAs are involved in the crucial processes of disease progression and have emerged as
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …

Multidrug resistance (MDR) of cancer is a persistent problem in chemotherapy. Scientists
have considered the overexpressed efflux transporters responsible for MDR and …

RNA nanotechnology is the bottom-up self-assembly of nanometer-scale architectures,
resembling LEGOs, composed mainly of RNA. The ideal building material should be (1) …

Malignant tumor is still a leading threat to human health. Despite the rapid development of
targeted therapeutic strategies, any treatment specifically acting on single target would …

MicroRNAs (miRNAs) are short (18–25 nt), non-coding, widely conserved RNA molecules
responsible for regulating gene expression via sequence-specific post-transcriptional …

Hydrogels are promising candidates for the delivery of therapeutics in the treatment of
human cancers. Regarding to the biocomaptiiblity, high drug and encapsulation efficacy and …

Background Camptothecin (CPT) is one of the frequently used small chemotherapy drugs for
treating hepatocellular carcinoma (HCC), but its clinical application is limited due to severe …

Background Tumor microenvironment (TME) plays a vital role in the development of
hepatocellular carcinoma (HCC). Mounting evidence indicates that peripheral nerves could …