Fibronectin in cancer: friend or foe
TC Lin, CH Yang, LH Cheng, WT Chang, YR Lin… - Cells, 2019 - mdpi.com
The role of fibronectin (FN) in tumorigenesis and malignant progression has been highly
controversial. Cancerous FN plays a tumor-suppressive role, whereas it is pro-metastatic …
controversial. Cancerous FN plays a tumor-suppressive role, whereas it is pro-metastatic …
Dormancy and cancer stem cells: An enigma for cancer therapeutic targeting
S Talukdar, P Bhoopathi, L Emdad, S Das… - Advances in cancer …, 2019 - Elsevier
Dormancy occurs when cells remain viable but stop proliferating. When most of a cancer
population undergoes this phenomenon, the result is called tumor dormancy, and when a …
population undergoes this phenomenon, the result is called tumor dormancy, and when a …
RGD functionalized chitosan nanoparticle mediated targeted delivery of raloxifene selectively suppresses angiogenesis and tumor growth in breast cancer
Acidic pH is a crucial intrinsic property of the microenvironment of most solid tumors. Hence,
the use of pH sensitive tumor targeting nanoparticles is an attractive approach to enhance …
the use of pH sensitive tumor targeting nanoparticles is an attractive approach to enhance …
Functional design of pH-responsive folate-targeted polymer-coated gold nanoparticles for drug delivery and in vivo therapy in breast cancer
Background Curcumin has been widely used owing to its various medicinal properties
including antitumor effects. However, its clinical application is limited by its instability, poor …
including antitumor effects. However, its clinical application is limited by its instability, poor …
Intratumor heterogeneity and therapy resistance: Contributions of dormancy, apoptosis reversal (anastasis) and cell fusion to disease recurrence
R Mirzayans, D Murray - International journal of molecular sciences, 2020 - mdpi.com
A major challenge in treating cancer is posed by intratumor heterogeneity, with different sub-
populations of cancer cells within the same tumor exhibiting therapy resistance through …
populations of cancer cells within the same tumor exhibiting therapy resistance through …
Prostate cancer cell‐intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone
The latency associated with bone metastasis emergence in castrate‐resistant prostate
cancer is attributed to dormancy, a state in which cancer cells persist prior to overt lesion …
cancer is attributed to dormancy, a state in which cancer cells persist prior to overt lesion …
Resistance to anti-angiogenic therapies: a mechanism depending on the time of exposure to the drugs
C Montemagno, G Pagès - Frontiers in Cell and Developmental …, 2020 - frontiersin.org
Angiogenesis, the formation of new blood vessels from preexisting one, represents a critical
process for oxygen and nutrient supply to proliferating cells, therefore promoting tumor …
process for oxygen and nutrient supply to proliferating cells, therefore promoting tumor …
Non-coding RNAs as potential therapeutic targets in breast cancer
Paradigm shifting studies especially involving non-coding RNAs (ncRNAs) during last few
decades have significantly changed the scientific perspectives regarding the complexity of …
decades have significantly changed the scientific perspectives regarding the complexity of …
The life cycle of polyploid giant cancer cells and dormancy in cancer: Opportunities for novel therapeutic interventions
Recent data suggest that most genotoxic agents in cancer therapy can lead to shock of
genome and increase in cell size, which leads whole genome duplication or multiplication …
genome and increase in cell size, which leads whole genome duplication or multiplication …
Tumor dormancy and slow-cycling cancer cells
Cancer cell heterogeneity is a universal feature of human tumors and represents a
significant barrier to the efficacy and duration of anticancer therapies, especially targeted …
significant barrier to the efficacy and duration of anticancer therapies, especially targeted …