The review of alpha‐linolenic acid: Sources, metabolism, and pharmacology

Q Yuan, F Xie, W Huang, M Hu, Q Yan… - Phytotherapy …, 2022 - Wiley Online Library
α‐linolenic acid (ALA, 18: 3n‐3) is a carboxylic acid composed of 18 carbon atoms and three
cis double bonds, and is an essential fatty acid indispensable to the human body. This study …

Cytochrome P450-derived linoleic acid metabolites EpOMEs and DiHOMEs: a review of recent studies

K Hildreth, SD Kodani, BD Hammock, L Zhao - The Journal of nutritional …, 2020 - Elsevier
Linoleic acid (LA) is the most abundant polyunsaturated fatty acid found in the Western diet.
Cytochrome P450-derived LA metabolites 9, 10-epoxyoctadecenoic acid (9, 10-EpOME), 12 …

The composition, extraction, analysis, bioactivities, bioavailability and applications in food system of flaxseed (Linum usitatissimum L.) oil: A review

J Yang, C Wen, Y Duan, Q Deng, D Peng… - Trends in Food Science …, 2021 - Elsevier
Abstract Background Flaxseed (Linum usitatissimum L.) oil is an excellent functional oil
containing various unsaturated fatty acids, mainly composed of linolenic acid, which is …

[HTML][HTML] Important roles of linoleic acid and α-linolenic acid in regulating cognitive impairment and neuropsychiatric issues in metabolic-related dementia

OY Kim, J Song - Life Sciences, 2024 - Elsevier
Metabolic syndrome (MetS), which is characterized by insulin resistance, high blood
glucose, obesity, and dyslipidemia, is known to increase the risk of dementia accompanied …

Correlations between α-linolenic acid-improved multitissue homeostasis and gut microbiota in mice fed a high-fat diet

X Gao, S Chang, S Liu, L Peng, J Xie, W Dong, Y Tian… - Msystems, 2020 - Am Soc Microbiol
Previous studies have shown that α-linolenic acid (ALA) has a significant regulatory effect on
related disorders induced by high-fat diets (HFDs), but little is known regarding the …

How important are fatty acids in human health and can they be used in treating diseases?

LMT Dicks - Gut Microbes, 2024 - Taylor & Francis
Most of the short-chain fatty acids (SCFAs) are produced by Bifidobacterium, Lactobacillus,
Lachnospiraceae, Blautia, Coprococcus, Roseburia, Facealibacterium and Oscillospira …

Plasma and serum oxylipin, endocannabinoid, bile acid, steroid, fatty acid and nonsteroidal anti-inflammatory drug quantification in a 96-well plate format

TL Pedersen, IJ Gray, JW Newman - Analytica Chimica Acta, 2021 - Elsevier
The goal of this research was to develop a high-throughput, cost-effective method for
metabolic profiling of lipid mediators and hormones involved in the regulation of …

[HTML][HTML] Bioactive lipids and their derivatives in biomedical applications

J Park, J Choi, DD Kim, S Lee, B Lee… - Biomolecules & …, 2021 - ncbi.nlm.nih.gov
Lipids, which along with carbohydrates and proteins are among the most important nutrients
for the living organism, have a variety of biological functions that can be applied widely in …

The influence of the western diet on microbiota and gastrointestinal immunity

V Las Heras, S Melgar, J MacSharry… - Annual Review of …, 2022 - annualreviews.org
Diet exerts a major influence upon host immune function and the gastrointestinal microbiota.
Although components of the human diet (including carbohydrates, fats, and proteins) are …

Effects of grape seed oil supplementation to broilers diets on growth performance, meat fatty acids, health lipid indices and lipid oxidation parameters

RP Turcu, TD Panaite, AE Untea, PA Vlaicu, IA Badea… - Agriculture, 2021 - mdpi.com
The purpose of this study was to evaluate the effects of grape seed oil (GSO)
supplementation to broilers fed polyunsaturated fatty acids (PUFA)-enriched diets on growth …