Advances in porous silicon–based nanomaterials for diagnostic and therapeutic applications

T Tieu, M Alba, R Elnathan… - Advanced …, 2019 - Wiley Online Library
This review provides a perspective on porous silicon (pSi)–based nanomaterials including
nanoparticles, nanowires, and thin films, that are currently being used in advanced therapy …

The application of inorganic nanoparticles in molecular targeted cancer therapy: EGFR targeting

M Sun, T Wang, L Li, X Li, Y Zhai, J Zhang… - Frontiers in …, 2021 - frontiersin.org
Epidermal growth factor receptor (EGFR) is an anticancer drug target for a number of
cancers, such as non-small cell lung cancer. However, unsatisfying treatment effects, terrible …

Systematic evaluation of transferrin-modified porous silicon nanoparticles for targeted delivery of doxorubicin to glioblastoma

M Luo, G Lewik, JC Ratcliffe, CHJ Choi… - … applied materials & …, 2019 - ACS Publications
There is a dire need to develop more effective therapeutics to combat brain cancer such as
glioblastoma multiforme (GBM). An ideal treatment is expected to target deliver …

A targeted erythrocyte membrane-encapsulated drug-delivery system with anti-osteosarcoma and anti-osteolytic effects

X Wu, X Zhang, W Feng, H Feng, Z Ding… - … Applied Materials & …, 2021 - ACS Publications
Chemotherapy is one of the main treatment methods for osteosarcoma. However,
conventional chemotherapy lacks targeting properties, and its long-term and extensive use …

Recent advances in surface engineering of porous silicon nanomaterials for biomedical applications

Y Jung, Y Huh, D Kim - Microporous and Mesoporous Materials, 2021 - Elsevier
Surface engineering of the nanomaterials opens a new era of their biomedical applications.
To date, various kinds of nanoparticles and their surface engineering techniques have been …

29Si Isotope-Enriched Silicon Nanoparticles for an Efficient Hyperpolarized Magnetic Resonance Imaging Probe

J Kim, D Jo, SH Yang, CG Joo, N Whiting… - … Applied Materials & …, 2021 - ACS Publications
Silicon particles have garnered attention as promising biomedical probes for hyperpolarized
29Si magnetic resonance imaging and spectroscopy. However, due to the limited levels of …

Gadolinium silicate-coated porous silicon nanoparticles as an MRI contrast agent and drug delivery carrier

JH Jin, H Um, JH Oh, Y Huh, Y Jung, D Kim - Materials Chemistry and …, 2022 - Elsevier
A nano-formulation based on gadolinium silicate-coated porous silicon nanoparticles
(pSiNPs) is newly disclosed as an MRI contrast agent and drug delivery carrier. In this study …

Stimuli‐Responsive Lanthanide‐Based Smart Luminescent Materials for Optical Encoding and Bio‐applications

Y Yang, P Su, Y Tang - ChemNanoMat, 2018 - Wiley Online Library
Lanthanide based luminescent materials have attracted extensive attention in a wide range
of fields including chemistry, biology and logic due to the narrow emission band, long decay …

[HTML][HTML] Porous silicon microparticles as efficient carriers for immunologic adjuvants

A Sambugaro, M Donini, E Chistè, M Scarpa… - Journal of Drug Delivery …, 2024 - Elsevier
In this work we report a first-time combination of porous silicon (pSi) particles with the
immunologic adjuvant Pam3CSK4, a TLR 1/2 agonist, as a tool for immunotherapy. pSi is a …

One-pot hydrothermal preparation of gadolinium-doped silicon nanoparticles as a dual-modal probe for multicolor fluorescence and magnetic resonance imaging

S Li, F Wang, XW He, WY Li, YK Zhang - Journal of Materials Chemistry …, 2018 - pubs.rsc.org
At present, multimodal probes for fluorescence and magnetic resonance imaging based on
gadolinium-silicon hybrid nanoparticles have been reported. However, the existing …