BACKGROUND Nearly every plant, animal, and environment on earth is host to a diverse
community of microorganisms that influence each other and their environment …

Imaging mass spectrometry has become a mature molecular mapping technology that is
used for molecular discovery in many medical and biological systems. While powerful by …

Neutrophils and macrophages are critical to the innate immune response, but cooperative
mechanisms used by these cells to combat extracellular pathogens are not well understood …

Cellular organization and functions encompass multiple scales in vivo. Emerging high-plex
imaging technologies are limited in resolving subcellular biomolecular features. Expansion …

Mass spectrometry imaging (MSI) is a powerful tool for label-free mapping of the spatial
distribution of proteins in biological tissues. We have previously demonstrated imaging of …

Molecular imaging has the potential to unearth important spatial and temporal relationships
in biological systems, including intercellular signaling as well as environmentally-cued …

Label-free spatial mapping of the noncovalent interactions of proteins in their tissue
environment has the potential to revolutionize life sciences research by providing …

Unraveling the complexity of biological systems relies on the development of new
approaches for spatially resolved proteoform‐specific analysis of the proteome. Herein, we …

Top‐down proteomics is emerging as a preferred approach to investigate biological
systems, with objectives ranging from the detailed assessment of a single protein …

Staphylococcus aureus is responsible for a substantial number of invasive infections
globally each year. These infections are problematic because they are frequently recalcitrant …