Human chitotriosidase: catalytic domain or carbohydrate binding module, who's leading HCHT's biological function

O Crasson, G Courtade, RR Léonard, FL Aachmann… - Scientific reports, 2017 - nature.com
Chitin is an important structural component of numerous fungal pathogens and parasitic
nematodes. The human macrophage chitotriosidase (HCHT) is a chitinase that hydrolyses …

Serum YKL-40 in young patients with β-thalassemia major: Relation to hepatitis C virus infection, liver stiffness by transient elastography and cardiovascular …

MA El-Asrar, NS Elbarbary, EAR Ismail… - Blood Cells, Molecules …, 2016 - Elsevier
Background YKL-40 is an inflammatory glycoprotein involved in endothelial dysfunction and
elevated in sera of patients with liver diseases. Aim To determine serum YKL-40 among 50 …

Evaluation of Chitotriosidase as a marker of inflammatory status in critical limb ischemia

RA Ciocan, C Drugan, CD Gherman… - Annals of Clinical & …, 2017 - Assoc Clin Scientists
Background Chitotriosidase is an enzyme secreted by activated macrophages. This study
aims to investigate the usefulness of circulating chitotriosidase activity as a marker of …

Serum chitotriosidase: a circulating biomarker in polycythemia vera

I Krecak, V Gveric-Krecak, P Roncevic… - …, 2018 - Taylor & Francis
Objectives: Serum chitotriosidase activity (CHIT1) is a biomarker of macrophage activation
with an important role in inflammation-induced tissue remodeling and fibrosis. Macrophages …

Serum chitotriosidase and YKL-40 in acute pancreatitis: Reliability as prognostic markerfor disease severity and correlation with inflammatory markers

EÜ Çetin, F Kamiş, AU Çetin… - Turkish journal of …, 2021 - journals.tubitak.gov.tr
Background/aim: Chitotriosidase and YKL-40, also called chitinase 3-like protein 1, are
homologs of family 18 glycosyl hydrolases, secreted by human macrophages and …

An NMR investigation of lytic polysaccharide monooxygenases

G Courtade - 2018 - ntnuopen.ntnu.no
Bioeconomy requires sustainable sources of biomass (eg chitin and cellulose) to use as
energy, feed and biomaterials. In the quest of biomass conversion, lytic polysaccharide …