Protein tyrosine kinases (PTKs) are a class of proteins with tyrosine kinase activity that
phosphorylate tyrosine residues of critical molecules in signaling pathways. Their basal …

Abstract The Emergence of Long Non-coding RNAs (lncRNAs) as Key Regulators in Diverse
Biological Processes: A Paradigm Shift in Understanding Gene Expression and its Impact on …

Statement of Retraction The Publisher of the journal Bioengineered, have retracted the
following article: Miao YQ, Chen W, Zhou J, Shen Q, Sun Y, Li T, Wang SC. N (6)-adenosine …

Background Co-occurring genomic alterations identified downstream main oncogenic
drivers have become more evident since the introduction of next-generation sequencing …

Background Glioblastoma (GBM) is an aggressive tumor that frequently exhibits gain of
chromosome 7, loss of chromosome 10, and aberrantly activated receptor tyrosine kinase …

Although the importance of histone methylation in epigenetics was first suggested more than
50 years ago, research into histone modifications conducted in the past decade has led to …

In years of research on classical pathways, the composition, information transmission
mechanism, crosstalk with other pathways, and physiological and pathological effects of …

Background: Non-small cell lung cancer (NSCLC), caused by abnormal gene drive, may
have primary drug resistance after treatment with tyrosine kinase inhibitors (EGFR-TKIs) …

Colorectal cancer (CRC) is one of the most common gastrointestinal cancers that results in
death in worldwide. The Hedgehog (HH) signalling pathway regulates the initiation and …

Osimertinib, as a third-generation epidermal growth factor receptor (EGFR)-tyrosine kinase
inhibitor (TKI), targeting EGFR exon 19 deletions, L858R, and T790M, has shown robust …