Oxygen–Ozone therapy in the rehabilitation field: state of the art on mechanisms of action, safety andeffectiveness in patients with musculoskeletal disorders

A de Sire, F Agostini, L Lippi, M Mangone, S Marchese… - Biomolecules, 2021 - mdpi.com
In recent years, the interest in oxygen–ozone (O2O3) therapy application has considerably
increased in the field of rehabilitation. Despite its widespread use in common clinical …

Mechanisms of action of ozone therapy in emerging viral diseases: immunomodulatory effects and therapeutic advantages with reference to SARS-CoV-2

A Cenci, I Macchia, V La Sorsa, C Sbarigia… - Frontiers in …, 2022 - frontiersin.org
Medical oxygen-ozone (O2-O3) is a successful therapeutic approach accounting on the
assessed beneficial action of ozone in the range 30–45 μg/ml (expanded range 10–80 …

Insights on the mechanisms of action of ozone in the medical therapy against COVID-19

S Chirumbolo, L Valdenassi, V Simonetti… - International …, 2021 - Elsevier
An increasing amount of reports in the literature is showing that medical ozone (O 3) is used,
with encouraging results, in treating COVID-19 patients, optimizing pain and symptoms …

Science's Response to CoVID‐19

MJC Long, Y Aye - ChemMedChem, 2021 - Wiley Online Library
CoVID‐19 is a multi‐symptomatic disease which has made a global impact due to its ability
to spread rapidly, and its relatively high mortality rate. Beyond the heroic efforts to develop …

The Mito-Hormetic mechanisms of ozone in the clearance of SARS-CoV2 and in the COVID-19 therapy

S Chirumbolo, A Varesi, M Franzini, L Valdenassi… - Biomedicines, 2022 - mdpi.com
An increasing body of evidence in the literature is reporting the feasibility of using medical
ozone as a possible alternative and adjuvant treatment for COVID-19 patients, significantly …

[HTML][HTML] Benefits of ozone on mortality in patients with COVID-19: A systematic review and meta-analysis

W Shang, Y Wang, G Wang, D Han - Complementary Therapies in …, 2023 - Elsevier
Abstract Background The Coronavirus disease-2019 (COVID-19) pandemic continues, and
the death toll continues to surge. Ozone therapy has long been used in the treatment of a …

Ozone as an adjuvant therapy for COVID-19: A systematic review and meta-analysis

DS Budi, IF Rofananda, NR Pratama, H Sutanto… - International …, 2022 - Elsevier
Objective Ozone adjuvant in COVID-19 management showed conflicting results in prior
studies. Here, we aimed to comprehensively evaluate benefits and side effects of ozone as …

[HTML][HTML] Clinical effectiveness of medical ozone therapy in COVID-19: the evidence and gaps map

MEG Serra, J Baeza-Noci, CVM Abdala… - Medical gas …, 2023 - journals.lww.com
Ozone therapy (OT), a medical procedure, has been showing good results during the
coronavirus disease (COVID-19). We aimed to build an evidence and gaps map (EGM) of …

Evaluation of the potential impact of medical ozone therapy on Covid-19: a review study

E Ogut, K Armagan - Ozone: Science & Engineering, 2023 - Taylor & Francis
The key objective of this review is to summarize the available information on the effects of
medical ozone therapy in COVID-19 and its therapeutic potentials. An electronic literature …

Compassionate Use of Rectal Ozone (O3) in Severe COVID-19 Pneumonia: a Case-Control Study

ME Fernández-Cuadros, MJ Albaladejo-Florín… - SN comprehensive …, 2021 - Springer
Objectives To evaluate effect of rectal ozone in severe COVID-19 pneumonia and to
compare it to standard of care (SOC). Material and Methods In a case-control study, 14 …